Results 41 to 50 of about 151,675 (256)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Evaluation of SDGSAT-1 MII data in total suspended matter estimation in clear to extremely turbid rivers

International Journal of Digital Earth
The Multispectral Imager (MII) onboard the newly launched SDGSAT-1 holds significant promise for monitoring and understanding variations in water quality within nearshore water systems, with an impressive spatial resolution of 10 m, seven spectral bands ...
Shenglei Wang, Zichen Mao, Bing Zhang, Xiaolong Yu, Fenqi Zhao, Xiaofei Song, Changyong Dou, Fangfang Zhang, Junsheng Li   +8 more
doaj   +1 more source

A deep relearning method based on the recurrent neural network for land cover classification

GIScience & Remote Sensing, 2022
Recent developments in deep learning (DL) techniques have provided a series of new methods for land cover classification. However, most DL-based methods do not consider the rich spatial association of land cover classes embedded in remote sensing images.
Yunwei Tang, Fang Qiu, Bangjin Wang, Di Wu, Linhai Jing, Zhongchang Sun   +5 more
doaj   +1 more source

Spatial Population Distribution Data Disaggregation Based on SDGSAT-1 Nighttime Light and Land Use Data Using Guilin, China, as an Example

Remote Sensing, 2023
A high-resolution population distribution map is crucial for numerous applications such as urban planning, disaster management, public health, and resource allocation, and it plays a pivotal role in evaluating and making decisions to achieve the UN ...
Can Liu, Yu Chen, Yongming Wei, Fang Chen   +3 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

A systematic study of interactions between sustainable development goals (SDGs) in Hainan Island

Scientific Reports
The 2030 Agenda for Sustainable Development issued by the United Nations is an important foundation for countries to achieve common economic, social and environmental development.
Linyan Bai, Xinjian Wang, Li Zhang, Jianzhong Feng, Jingjuan Liao, Bowei Chen, Penglong Wang, Xinyi Zhang   +7 more
doaj   +1 more source

A Review of Research on the Stability of Fine-Grained Sediments in Debris Flows

Geosciences
Fine-grained sediments in debris flows refer to Quaternary sediments with grain sizes smaller than 2 mm. Their stability is closely related to the initial water threshold that triggers the debris flows and thus controls the density, scale, and damage of ...
Qinjun Wang, Jingyi Yang, Wentao Xu, Boqi Yuan, Chaokang He   +4 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source