Results 61 to 70 of about 1,229,835 (284)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Spatiotemporal Analysis of Photovoltaic Potential in Ordos City Based on an Improved CRITIC Method

Land
In view of the contradiction between the still-high energy consumption in Ordos and the increasingly urgent carbon-neutral goal, the adjustment of energy structures has begun, and strategic planning of photovoltaic facility construction critically ...
Yifei Guo, Lanwei Zhu, Liduo Dou, Yuxin He, Meiqing Wu   +4 more
doaj   +1 more source

Transformations to achieve the Sustainable Development Goals Includes the SDG Index and Dashboards. Sustainable Development Report 2019 [PDF]

, 2019
The Sustainable Development Report 2019 presents an updated SDG Index and Dashboards with a refined assessment of countries’ distance to SDG targets. The report has been successfully audited for the first time by the European Commission Joint Research ...
Fuller, G., Kroll, C., Lafortune, G., Sachs, J., Schmidt-Traub, G.   +4 more
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

MPG-Net: A Semantic Segmentation Model for Extracting Aquaculture Ponds in Coastal Areas from Sentinel-2 MSI and Planet SuperDove Images

Remote Sensing
Achieving precise and swift monitoring of aquaculture ponds in coastal regions is essential for the scientific planning of spatial layouts in aquaculture zones and the advancement of ecological sustainability in coastal areas.
Yuyang Chen, Li Zhang, Bowei Chen, Jian Zuo, Yingwen Hu   +4 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Financing the Post-2015 Sustainable Development Goals: A Rough Roadmap [PDF]

, 2014
We regroup the main types of global development finance into three clusters: concessional public finance (including domestic taxes), public borrowing on market-related terms, and private finance.
Andrew Rogerson, Annalisa Prizzon
core  

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

SPT-UNet: A Superpixel-Level Feature Fusion Network for Water Extraction from SAR Imagery

Remote Sensing
Extracting water bodies from synthetic aperture radar (SAR) images plays a crucial role in the management of water resources, flood monitoring, and other applications.
Teng Zhao, Xiaoping Du, Chen Xu, Hongdeng Jian, Zhipeng Pei, Junjie Zhu, Zhenzhen Yan, Xiangtao Fan   +7 more
doaj   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source