The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi +11 more
wiley +1 more source
Consumers' Knowledge, Attitudes, and Sensory Perception of Soilless-Grown Strawberries in the Context of Sustainable Diet. [PDF]
Calella P +6 more
europepmc +1 more source
Genetic manipulation of anti-nutritional factors in major crops for a sustainable diet in future. [PDF]
Duraiswamy A +10 more
europepmc +1 more source
Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou +14 more
wiley +1 more source
Development and Validation of a Multidimensional Consumer Assessment Framework for Alternative-Ingredient Bakery and Confectionery Products: Implications for Nutrition Methodology and Sustainable Diet Research. [PDF]
Dicu AM +8 more
europepmc +1 more source
Does Nepal Have the Agriculture to Feed Its Population with a Sustainable Diet? Evidence from the Perspective of Human-Land Relationship. [PDF]
Liu Y, Yang Y, Zhang C, Xiao C, Song X.
europepmc +1 more source
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang +9 more
wiley +1 more source
Healthy and Sustainable Diet Index: Development, Application and Evaluation Using Image-Based Food Records. [PDF]
Harray AJ +6 more
europepmc +1 more source
The increase in the world population and the resulting increase in consumption levels, the limitation and inefficient use of resources available in nature may cause dangers for future generations. It is known that our current food system causes global greenhouse gas emissions and has negative effects on our planet.
Karabıyık, Dilay +2 more
openaire +1 more source
SAT1‐Induced Spermidine Depletion Potentiates Food Allergy
Spermidine depletion, driven by upregulated spermidine/spermine N1‐acetyltransferase (SAT1), potentiates food allergy by promoting mast cell degranulation through autophagy suppression. SAT1 physically interacts with the long noncoding RNA Cdk19os to inhibit Atg5 and Atg7, disrupting autophagic flux.
Manman Liu +8 more
wiley +1 more source

