Results 91 to 100 of about 2,561,805 (283)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Double dividend : promoting good nutrition and sustainable consumption through healthy school meals [PDF]

, 2012
This report, produced by the Sustainable Consumption Roundtable tackles the issues surrounding promoting good nutrition and sustainable consumption through healthy school meals.Publisher ...
Soil Association, Green, Michael, Morgan, Kevin, Sonnino, Roberta, Pearce, Hannah, Noble, Emma, Sustainable Consumption Roundtable (Great Britain)   +6 more
core   +2 more sources

Agrobiodiversity and a sustainable food future

Nature Plants, 2017
The biodiversity of food plants is vital for humanity's capacity to meet sustainability challenges. This goal requires the rigorous integration of plant, environmental, social and health sciences. It is coalescing around four thematic cornerstones that are both interdisciplinary and policy relevant.
Zimmerer, Karl S., Haan, Stef de
openaire   +3 more sources

Using the Perspectives of Kentucky Family and Consumer Sciences Extension Agents to Develop a Sustainable Eating Curriculum

Journal of Human Sciences and Extension
Sustainable eating may benefit both the environment and human health. Currently, no Extension programs addressing healthy and sustainable eating are available that target adults in communities.
Lindley Barker , Heather Norman-Burgdolf, Annie Koempel, Katie Pickford, Tammy Stephenson, Dawn Brewer   +5 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Challenges and future perspectives of sustainable supplements, functional foods, and nutrigenomics in athletic performance

Human Movement
Nutrition plays a key role in the lives of athletes, sustaining and enhancing sports performance by significantly influencing their performance and general well-being.
Flores Naselli, Paola Sofia Cardinale, Sonya Vasto, Patrizia Proia, Sara Baldassano, Fabio Caradonna   +5 more
doaj   +1 more source

Campaign education and communication to the potential consumers of brewers' spent grain (BSG)-added food products as sustainable foods. [PDF]

Heliyon, 2023
Naibaho J, Korzeniowska M, Julianti E, Sebayang NS, Yang B.   +4 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source