Results 61 to 70 of about 2,561,805 (283)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Strengths and weaknesses of food eco-labeling: a review

Frontiers in Nutrition
Food labeling is increasingly expanding and adding more information to the food package. There is strong evidence about nutrition labeling effectiveness in driving food choice, especially if displayed in the front of package (FoP).
Ornella Tiboni-Oschilewski, Magdalena Abarca, Fabiana Santa Rosa Pierre, Alice Rosi, Beatrice Biasini, Davide Menozzi, Francesca Scazzina   +6 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

The overlooked importance of food disadoption for the environmental sustainability of new foods

Environmental Research Letters, 2021
With human food production a major driver of global environmental change, there is increasing recognition of the importance of shifting towards more sustainable dietary patterns.
Richard S Cottrell, Jason Maier, Danielle M Ferraro, Gordon D Blasco, Roland Geyer, Halley E Froehlich, Benjamin S Halpern   +6 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Designing Sustainable Food Systems [PDF]

Proceedings of the 2017 CHI Conference Extended Abstracts on Human Factors in Computing Systems, 2017
There is significant interest in designing technologies for the food system, from agricultural modeling tools to apps enabling humans to assess nutritional value of various food choices to drones for pest detection. However, a good food system must be a sustainable one.
Ankita Raturi, Juliet Norton, Bill Tomlinson, Eli Blevis, Lynn Dombrowski   +4 more
openaire   +1 more source

Sustainable development and UK faith groups : two sides of the same coin? : a survey of UK faith communities’ sustainable development activities and next steps for the future [PDF]

, 2012
English language version of 'Datblygu cynaliadwy a grwpiau ffydd y DU : dwy ochr yr un geiniog? : arolwg o weithgareddau datblygu cynaliadwy cymunedau ffydd y DU a’r camau nesaf ar gyfer y dyfodol'.A survey of UK faith communities’ sustainable ...
World Wildlife Fund UK, Sustainable Development Commission   +1 more
core   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The future of sustainable food production [PDF]

Annals of the New York Academy of Sciences, 2010
By the year 2050, the number of people on Earth is expected to increase from the current 6.7 to 9.2 billion. What is the best way to produce enough food to feed all these people? If we continue with current farming practices, vast amounts of wilderness will be lost, millions of birds and billions of insects will die, farm workers will be at increased ...
Ronald, Pamela, Adamchak, Raoul
openaire   +3 more sources