Results 111 to 120 of about 302,151 (264)
Role of change leadership in attaining sustainable growth and curbing poverty: A case of Pakistan tourism industry. [PDF]
Front Psychol, 2022 Bashir F, Tahir Z, Aslam A.
europepmc +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
The Impact of Sustainable Growth and Sustainable Environment on Public Health: A Study of GCC Countries. [PDF]
Front Public Health, 2022 Khan MN, Aziz G, Khan MS.
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
A Comprehensive Analysis of Circular Fashion in Small Clothing Firms
RAC: Revista de Administração ContemporâneaObjective: this study aims to highlight the potential of the circular economy in small clothing companies, following the aspect of sustainable development, and that have undertaken some prior pro-sustainability action, under the notion that everything ...
Thomás Czrnhak +2 more
doaj +1 more source
Economic Growth And Sustainable Development: Sustainability or Sustainable Development?
Refuge: Canada's Journal on Refugees, 1996 Depuis les trois dernieres decades, le debat sur le developpement durable s'est caracterise par une etroite politique de developpement et de l'environnement laissant une large marge aux interpretations. Ces interpretations ne correspondent pas souvent a celles de ceux qui utilisent les forces du marche ainsi que les multinationales pour mieux ...
openaire +3 more sources
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
[Sustainable Growth: Does Germany Need an Investment Programme?] [PDF]
Wirtschaftsdienst, 2021 ZG Überblick.
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source