Results 51 to 60 of about 1,850,484 (311)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Sustainable urban growth [PDF]

, 2022
Diese Dissertation untersucht die Determinanten für ein nachhaltiges und sozial optimales Wachstum in den Städten. Zwei endogene Wachstumsmodelle untersuchen hierzu die Rolle von nichtmarktbasierten und marktbasierten Politikeingriffen. Jedes Modell fügt dabei dem städtischen Nachhaltigkeitsdiskurs sein eigenes Puzzleteil hinzu.
openaire   +2 more sources

Rediscovering local breeds of naturally free-range hens: a survey on Italian consumers’ awareness of hen welfare and egg purchasing behavior

BMC Veterinary Research
Background Egg production is dominated by the use of conventional cage systems, but the increasing awareness of consumers about animal welfare has led to a shift toward cage-free and free-range systems.
Elena Gosso, Greta Falavigna, Valentina Lamonica, Cristina Lamberti, Simona Cirrincione, Laura Cavallarin, Maria Gabriella Giuffrida, Achille Schiavone   +7 more
doaj   +1 more source

What the council of economic advisors need to know about sustainable development [PDF]

, 2007
The decision by Alex Salmond to appoint a Council of Economic Advisors to move economic decision making away from purely political rationale is particularly welcome given the new administration’s commitment to sustainable economic growth as the ...
Mathieson, Scot, McRory, Eric, Richards, Caspian, Williams, Evan   +3 more
core  

Youth opportunity spaces in low-emission dairy development in Kenya: Research findings and policy recommendations [PDF]

, 2020
The dairy sector in Kenya produces over 4 billion liters of milk per year and supports 1.3 million producer households with a vital contribution to incomes and nutrition. However, total national production fails to meet demand.
Bullock, Renee M., Crane, Todd A.
core  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Growing green?: co-creating an evidence-based model of SME engagement [PDF]

, 2017
Topic: This paper reports on our experiences in running a pilot ESRC Impact Acceleration Account (IAA) project that addresses the issue of ‘sustainable growth’ by engaging SME owners and managers in facilitated workshop discussions on this important, yet
Blundel, Richard, Fawcett, Tina, Hampton, Sam, Shaw, Chris, Westall, Andrea   +4 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Sustainable growth in complex networks

, 2010
Based on the empirical analysis of the dependency network in 18 Java projects, we develop a novel model of network growth which considers both: an attachment mechanism and the addition of new nodes with a heterogeneous distribution of their initial ...
C. J. Tessone, F. Schweitzer, Faloutsos M. Faloutsos P. Faloutsos C., Gamma E., M. M. Geipel, Saichev A., Simon H., Valverde S., Valverde S.   +8 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source