Results 71 to 80 of about 7,210,465 (281)
Путеводитель предпринимателя, 2020 In modern conditions of instability of the external business environment, the growth of companies includes the identification of factors that affect the development of the company and its stability.
A. U. Kidyaeva
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
On Green Growth with Sustainable Capital
, 2020 We develop an endogenous growth model to address a long standing question whether sustainable green growth is feasible by re-allocating resource use between green (natural) and man-made (carbon intensive) capital. Although the model is general we relate it to the UK’s green growth policy objective.
Basu, Parantap, Jamasb, Tooraj
openaire +5 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Scientific ReportsThe concept of niche similarity is crucial for understanding species invasions. An in-depth understanding of different niches can aid in developing effective control strategies, not only at the community level but also in population interactions. In this
Lina Cui +5 more
doaj +1 more source
Journal of Development Economics, 2008 We identify structural breaks in economic growth in 140 countries and use these to define "growth spells:" periods of high growth preceded by an upbreak and ending either with a downbreak or with the end of the sample. Growth spells tend to be shorter in African and Latin American countries than elsewhere.
Jonathan David Ostry +2 more
openaire +2 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Sustainable development in government 2008 : challenges for government [PDF]
, 2012 Our seventh annual SDiG assessment found good overall progress by the UK Government, especially on targets for water, waste and travel, though reductions in carbon emissions from offices were still not on track.Publisher ...
Sustainable Development Commission
core +2 more sources
COVID-19 vaccine race – the shadow of political and multinational interests
Cogent Social SciencesThe COVID-19 pandemic caused global disruption in 2020, throwing the world into an unprecedented health crisis with unpredicted socio-economic consequences.
Daniel Rajmil, Lucía Morales, Toni Aira
doaj +1 more source