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The General Theory of Scientific Variability for Technological Evolution
SciThe proposed general theory of scientific variability for technological evolution explains one of the drivers of technological change for economic progress in human society. Variability is the predisposition of the elements in systems to assume different
Mario Coccia
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Scientific ReportsForests and their provision of ecosystem services are endangered by climate change. Tree-species diversification has been identified as a key adaptation strategy to balance economic risks and returns in forest stands.
Jasper M. Fuchs +5 more
doaj +1 more source
Is Africa's Recent Growth Sustainable? [PDF]
International Economic Journal, 2013 AbstractIn this paper we argue that the answer, to the question of whether Africa's recent growth is sustainable, is yes. Our optimism rests on the finding that differences in the level of institutional quality predict cross-country variation in African economic growth during the period 1995–2011. This finding is quite robust.
Andersen, Thomas Barnebeck +1 more
openaire +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Attaining the 2030 Sustainable Development Goal of Decent Work and Economic Growth
, 2022 Attaining the 2030 Sustainable Development Goal of Decent Work and Economic Growth focuses on Sustainable Development Goal number eight (SDG8): inclusive and sustainable economic growth and productive employment for all.
Hales, Rob, Birdthistle, Naomi
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Managing Growth and Sustainable Tourism Governance in Asia and the Pacific
, 2017 This publication released on the occasion of the International Year for Sustainable Tourism for Development 2017, focuses on sustainable-tourism governance approaches that have helped to realize tourism’s potential to contribute to economic growth and ...
Scott, Noel
core +2 more sources