Results 41 to 50 of about 3,959,814 (238)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Nutrition of host plants influence the infectivity of nucleopolyhedrovirus to polyphagous caterpillar, Hyphantria cunea

Chemical and Biological Technologies in Agriculture
Plants play an important role in interactions between insect herbivores and their pathogens. The ability of host plants to modify the infectivity of entomopathogens in herbivorous insects has been widely documented.
Xudong Zhao, Yishu Geng, Heng Qiao, Yu Liu, Tianyi Hu, Wenxuan Xu, Dejun Hao   +6 more
doaj   +1 more source

Unlocking the past: key lessons in human-environment dynamics through cultural heritage analysis [PDF]

Urbanization, Sustainability and Society
PurposeThis paper aims to understand human-environment interactions in urban development over time by using historical data, cultural heritage and local knowledge to reduce risk exposure of local communities, prepare for disasters and enhance recovery ...
Giovanni Gugg, Mariana Oliveira, Gabriella Duca   +2 more
doaj   +1 more source

Molecular Characterization and Genetic Diversity of Ginkgo (Ginkgo biloba L.) Based on Insertions and Deletions (InDel) Markers

Plants, 2023
As a “living fossil”, ginkgo (Ginkgo biloba L.) has significant ornamental, medicinal, and timber value. However, the breeding improvement of ginkgo was limited by the lack of enough excellent germplasms and suitable molecular markers.
Dan Wang, Qi Zhou, Linlin Le, Fangfang Fu, Guibin Wang, Fuliang Cao, Xiaoming Yang   +6 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Development of an indirect immunofluorescence assay for PCV3 antibody detection based on capsid protein

Animal Diseases, 2021
Porcine circovirus type 3 (PCV3) is a novel porcine circovirus associated with porcine dermatitis and nephritis syndrome (PDNS), reproductive failure, and multisystemic inflammation.
Lun Yao, Chang Li, Junwei Wang, Yufang Cheng, Ahmed H. Ghonaim, Qi Sun, Xuexiang Yu, Weijie Niu, Shengxian Fan, Qigai He   +9 more
doaj   +1 more source

Accelerating the development and deployment of carbon capture and storage technologies : an innovation system perspective [PDF]

, 2011
In order to take up the twin challenge of reducing carbon dioxide (CO2) emissions, while meeting a growing energy demand, the potential deployment of carbon dioxide capture and storage (CCS) technologies is attracting a growing interest of policy makers ...
Dep of Sustainable Development, Options for a sustainable energy supply, van Alphen, K., Innovation Studies, Section Innovation Studies   +4 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Effects of retaining different number of mother bamboo on the growth and NSCs allocation of new-born seedlings in Phyllostachys edulis at different age

BMC Plant Biology
Background Non-structural carbohydrates (NSCs) are key substances for metabolic processes in plants, providing energy for growth, development, and responses to environmental stress.
Binao Zhou, Xu Zhang, Hanjiao Zhang, Wenjing Yao, Long Li, Shuyan Lin, Fuliang Cao   +6 more
doaj   +1 more source

Cryopreservation and Maturation Media Optimization for Enhanced Somatic Embryogenesis in Masson Pine (Pinus massoniana)

Plants
Pinus massoniana Lamb. (masson pine) is a critical species for afforestation in southern China but faces severe threats from pine wilt disease (PWD) caused by Bursaphelenchus xylophilus.
Qian Yang, Ying Lin, You-Mei Chen, Qi Fei, Jian-Ren Ye, Li-Hua Zhu   +5 more
doaj   +1 more source