Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Biofilm Dispersal in Bacillus velezensis FZB42 Is Regulated by the Second Messenger c-di-GMP
MicroorganismsCyclic diguanosine monophosphate (c-di-GMP) is a second messenger that plays a crucial role in regulating biofilm development, yet the role in Gram-positive bacteria remains elusive.
Meiyu Zhang +5 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Carbon sequestration potential of Tamanu (Calophyllum inophyllum) in Gunung Kidul, Yogyakarta [PDF]
BIO Web of ConferencesIndigenous tree species play an important yet underestimated role in tropical ecosystems’ carbon sequestration, mitigating global climate change. Tamanu (Calophyllum inophyllum), an indigenous tree species, is studied for its carbon sequestration ...
Hanafi Hano +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
A sustainable new deal : a stimulus package for economic, social and ecological recovery [PDF]
, 2012 Sustainable Development Commission's advice to Government on how to revive the UK's economy through a green recovery package.Publisher ...
Sustainable Development Commission
core +2 more sources
Maternal and paternal contributions to seed and seedling traits in Ginkgo Biloba hybrids
BMC Plant BiologyBackground Ginkgo biloba L. is a dioecious plant with a life history of billions of years, and hybridization is one of its main forms of generation replacement in nature.
Xiaoge Gao +5 more
doaj +1 more source
Complete plastome sequence of the Narcissus tazetta Var. chinensis: an important flower resource
Mitochondrial DNA. Part B. Resources, 2020 Narcissus tazetta var. chinensis is an important economic perennial herb in China. In this study, the complete plastid genome was assembled from the next-generation sequencing data. The circular genome is 159,376 bp long, and comprises a pair of inverted
Yongfu Li +7 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The complete chloroplast genome of Sorbus folgneri (C.K.Schneid.) Rehder (Rosaceae)
Mitochondrial DNA. Part B. Resources, 2019 Sorbus folgneri (C.K.Schneid.) Rehder is widely distributed tree species across China which can be used as medicine, building materials and ornamental plants. In this study, the complete chloroplast (cp) genome sequence of S.
Jing Qiu +5 more
doaj +1 more source