Results 31 to 40 of about 260,839 (311)

A heat shock 70kDa protein MaltHSP70-2 contributes to thermal resistance in Monochamus alternatus (Coleoptera: Cerambycidae): quantification, localization, and functional analysis

BMC Genomics, 2022
Background Heat Shock Proteins 70 (HSP70s) in insects act on a diverse range of substrates to assist with overcoming extreme high temperatures. MaltHSP70-2, a member of HSP70s, has been characterized to involve in the thermotolerance of Monochamus ...
Hui Li, Shouyin Li, Jin Chen, Lulu Dai, Ruixu Chen, Jianren Ye, Dejun Hao   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Innovation Habitat: Sustainable possibilities for the society [PDF]

, 2015
Contemporary society is moving in the core of a reality in which sustainability needs to be thought out and inserted through practices carried out in different dimensions of society, such as organizations, public and private institutions. This paper aims
Machado, Andreia de Bem, da Silva, Andreza Regina Lopes, Borba, Marcelo Leandro, Catapan, Araci Hack   +3 more
core   +1 more source

Steering for Sustainable Development Goals: A Typology of Sustainable Innovation [PDF]

, 2020
Process and product innovation are defined as an organizational ability to discover and translate creative approaches to solve multiple organizational problems.
Awan, Usama, Usama Awan
core   +1 more source

Sustainable Product Innovation and Consumer Communication [PDF]

, 2022
Sustainable product innovation and its communication with consumers are essential for the realisation of sustainability through sustainable consumption.
Shuyi Wang, Daizhong Su, Su, D, Wang, S
core   +1 more source

Identification and functional characterization of the histone acetyltransferase gene family in Bursaphelenchus xylophilus

BMC Genomics
Background Acetylation is a widely occurring post-translational protein modification in animals, plants, and microorganisms. Histone acetyltransferase (HATs) are positive regulators of acetylation and are responsible for the growth, development, and ...
Lichao Wang, Yajing Song, Ruocheng Sheng, Muhammad Faizan Latif, Ming Xu, Yang Wang, Min Li, Fengmao Chen   +7 more
doaj   +1 more source

Apigenin Extracts from Myrmecodia pendans and Their Potential Role in Coronary Heart Disease Mitigation [PDF]

BIO Web of Conferences
Myrmecodia pendans is an epiphytic plant indigenous to Papua that contains apigenin, a bioactive compound with antioxidant, anti- inflammatory, and vasodilatory properties.
Santoso Budi, Sarungallo Nirel Andisfyl, Wattimena Beatrix Melany, Anggono Willyanto, Setiawan Edwin   +4 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source