Results 51 to 60 of about 2,326,597 (280)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The impact of COVID-19 on the sustainable intensification of forage-based beef and dairy value chains in Colombia: a blessing and a curse

Tropical Grasslands-Forrajes Tropicales, 2022
The COVID-19 pandemic has exacerbated the difficulties associated with the need to transition the cattle sector in Latin America towards achieving sustainability and created a “double crisis” of pandemic and climate change.
Stefan Burkart, Manuel Díaz, Karen Enciso, Andrés Charry, Natalia Triana, Martín Mena, José Luis Urrea-Benítez, Irieleth Gallo Caro, Rein van der Hoek   +8 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Geospatial monitoring and analysis of agricultural drought to identify hotspots and risk assessment for Senegal

Geography and Sustainability
Agricultural drought, characterized by insufficient soil moisture crucial for crop growth, poses significant challenges to food security and economic sustainability, particularly in water-scarce regions like Senegal.
Gurjeet Singh, Narendra N. Das, P.V. Vara Prasad   +2 more
doaj   +1 more source

Sustainable Intensification of Maize in the Industrial Revolution: Potential of Nitrifying Bacteria and Archaea

Frontiers in Sustainable Food Systems, 2022
Sustainable intensification is a means that proffer a solution to the increasing demand for food without degrading agricultural land. Maize is one of the most important crops in the industrial revolution era, there is a need for its sustainable ...
Oluwatobi Esther Ayiti, Olubukola Oluranti Babalola   +1 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The Role of Agroecology in Sustainable Intensification

, 2015
‘Sustainable intensification’ is now often used to describe the future direction for agriculture and food production as a way to address the challenges of increasing global population, food security, climate change and resource conservation.
Lampkin, N.H., Vieweger, A., Gerrard, C., Smith, J., Creissen, H., Smith, L.G., Leake, A.R., Lloyd, S., Padel, S., Wolfe, M.S., Pearce, B.D., Girling, R.   +11 more
core   +1 more source

How much can sustainable intensification increase yields across South Asia? a systematic review of the evidence

Environmental Research Letters, 2020
Food security will become increasingly challenged over the coming decades, and sustainable intensification is often touted as an ideal way to increase yields while limiting negative environmental impacts.
Meha Jain, Divya Solomon, Hagan Capnerhurst, Anthony Arnold, Alice Elliott, Andrew T Kinzer, Collin Knauss, Maya Peters, Brett Rolf, Ari Weil, Charlotte Weinstein   +10 more
doaj   +1 more source

Intensification for redesigned and sustainable agricultural systems [PDF]

Science, 2018
The future of farming In the mid-20th century, food production from agriculture sharply increased worldwide; however, this was achieved through heavy use of agrochemicals. Extensive collateral damage from excessive use of pesticides, herbicides, and fertilizers has occurred to the wider environment.
openaire   +3 more sources