Results 91 to 100 of about 6,005,317 (331)

Surface microhardening studies on steels after high feed milling [PDF]

, 2018
The paper deals with the impact of high-speed machining production methods on the integrity of component surfaces. One has to point out that cutting conditions during machining have a significant impact on the final properties of surface and subsurface ...
Petrů, Jana, Zlámal, Tomáš, Čep, Robert, Špalek, František   +3 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Advanced Optimization of Drilling Parameters in Composite Materials: A Topsis-Based Approach for Enhanced Manufacturing Precision

Journal of Natural Fibers
Drilling natural fiber composite materials is challenging due to their anisotropic and heterogeneous structure, which often leads to delamination, thermal damage, and poor surface finish. The key objective of this study is to optimize drilling parameters
Mustapha Arslane, Mohamed Slamani, Abdelmalek Elhadi, Salah Amroune, Ugur Köklü, Madani Grine, Borhen Louhichi, Sabbah Ataya   +7 more
doaj   +1 more source

Sustainable Solutions for Machine Tools [PDF]

, 2017
Environmental, economic and social changes of any significant proportions cannot take place without a major shift in the manufacturing sector. In today’s manufacturing processes, economic efficiency is realised through high volumes with the use of specialised machine tools. Change in society, such as in the form of mobility and digitisation, requires a
Eckart Uhlmann, Klaus-Dieter Lang, Lukas Prasol, Simon Thom, Bernd Peukert, Stephan Benecke, Eduard Wagner, Fiona Sammler, Sebastian Richarz, Nils F. Nissen   +9 more
openaire   +1 more source

A comparison of processing techniques for producing prototype injection moulding inserts. [PDF]

, 2019
This project involves the investigation of processing techniques for producing low-cost moulding inserts used in the particulate injection moulding (PIM) process.
Ewart, Paul
core  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas, Connor A. Law, Joan A. Casey, Thomas Mosley, Rebecca F. Gottesman, Ramon Diaz‐Arrastia, Holly Elser, Andrea L. C. Schneider   +7 more
wiley   +1 more source

Analysis of Secondary Adhesion Wear Mechanism on Hard Machining of Titanium Aerospace Alloy [PDF]

, 2019
Titanium alloys are widely used in important manufacturing sectors such as the aerospace industry, internal components of motor or biomechanical components, for the development of functional prostheses.
Black, Davim, Joao Paulo Davim, Jorge Salguero Gomez, Juan Manuel Vazquez-Martinez, Moises Batista Ponce, Wright   +6 more
core   +2 more sources

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

On the Use of Compressed Air and Synthetic Biodegradable Cutting Fluid to Enhance the Surface Quality of WAAM–CMT Manufactured Low-Alloy Steel Parts During Post-Processing Milling with Different Cooling–Lubrication Strategies

Journal of Manufacturing and Materials Processing
Additive manufacturing (AM) stands out for its variable applications in terms of material, quality, and geometry. Wire Arc Additive Manufacturing (WAAM) is remarkable for producing large parts in reduced times when compared to other AM methods.
Déborah de Oliveira, Marcos Vinícius Gonçalves, Guilherme Menezes Ribeiro, André Luis Silva da Costa, Luis Regueiras, Tiago Silva, Abílio de Jesus, Lucival Malcher, Maksym Ziberov   +8 more
doaj   +1 more source