Results 81 to 90 of about 28,107 (312)

Life cycle assessment (LCA) applied to the process industry: a review [PDF]

, 2011
Purpose : Life cycle assessment (LCA) methodology is a well-established analytical method to quantify environmental impacts, which has been mainly applied to products. However, recent literature would suggest that it has also the potential as an analysis
Jacquemin, Leslie, Pontalier, Pierre-Yves, Sablayrolles, Caroline   +2 more
core   +6 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

On the Use of Compressed Air and Synthetic Biodegradable Cutting Fluid to Enhance the Surface Quality of WAAM–CMT Manufactured Low-Alloy Steel Parts During Post-Processing Milling with Different Cooling–Lubrication Strategies

Journal of Manufacturing and Materials Processing
Additive manufacturing (AM) stands out for its variable applications in terms of material, quality, and geometry. Wire Arc Additive Manufacturing (WAAM) is remarkable for producing large parts in reduced times when compared to other AM methods.
Déborah de Oliveira, Marcos Vinícius Gonçalves, Guilherme Menezes Ribeiro, André Luis Silva da Costa, Luis Regueiras, Tiago Silva, Abílio de Jesus, Lucival Malcher, Maksym Ziberov   +8 more
doaj   +1 more source

Sustainable machining: process energy optimisation of wire electrodischarge machining of Inconel and titanium superalloys [PDF]

, 2017
Process energy optimisation is vital in view of the environmental performance of electrodischarge machining (EDM). This research is focused on identifying the significant parameters that optimise the process energy consumption of wire EDM (WEDM) of ...
Antar, Mohammad, Chantzis, Dimitrios, DeSilva, Anjali K.M., Gamage, Janaka R.   +3 more
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Assessment of surface quality and damages induced during dry helical milling of hybrid composite fiber metal laminates

Materials Research Express
The present work investigates the effectiveness of helical milling for making holes with excellent surface quality in carbon fiber aluminum laminates (CARALL) under dry cutting conditions.
Satish Shenoy Baloor, Suleyman Cinar Cagan, Gururaj Bolar, Madhusudhan Balkundhi, Anoop Aroor Dinesh   +4 more
doaj   +1 more source

Tidal energy machines: A comparative life cycle assessment

, 2013
Marine energy in the UK is currently undergoing a period of exponential growth in terms of development and implementation. The current installed tidal energy capacity of around 4MW is expected to rise to provide up to 20% of the UK’s electricity demand ...
Callaghan J, Dedić N, Department for Environment, Food and Rural Affairs (DEFRA), Douglas CA, Forster P, Intergovernmental Panel on Climate Change (IPCC), Nylund N-O, Pham C, World Steel Association   +8 more
core   +1 more source

Generation of Micro Mechanical Devices Using Stereo Lithography [PDF]

, 2006
A high resolution machining setup for creating three-dimensional precision components from a UV-curable photo-resin has been developed. By using frequency-converted diode-pumped solid state lasers, functional micro-mechanical devices are directly ...
Himmelhuber, R., Neumeister, A., Stute, U., Temme, T.   +3 more
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

A comparison of processing techniques for producing prototype injection moulding inserts. [PDF]

, 2019
This project involves the investigation of processing techniques for producing low-cost moulding inserts used in the particulate injection moulding (PIM) process.
Ewart, Paul
core