Results 91 to 100 of about 28,107 (312)

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Evaluation of Cutting Forces and Temperatures in Micro-Milling of NiTi Alloys Using Finite Element Modeling

Журнал інженерних наук
Today, micro-milling of NiTi alloys is used to manufacture precision mechanisms, instrumentation, space technology, micro-electro-mechanical systems, biomedical devices, and implants. It is becoming increasingly widespread.
Nataliia Balytska, Oleh Tomashevskyi, Valentina Shadura   +2 more
doaj   +1 more source

Supply chain implications of sustainable design strategies for electronics products [PDF]

, 2012
Increasing legislative and consumer pressures on manufacturers to improve sustainability necessitates that manufacturers consider the overall life cycle and not be scope restricted in creating products.
Bateman, RJ, De Coster, R, Plant, AVC
core   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Enhancement of Machining Performance of Ti-6Al-4V Alloy Though Nanoparticle-Based Minimum Quantity Lubrication: Insights into Surface Roughness, Material Removal Rate, Temperature, and Tool Wear

Journal of Manufacturing and Materials Processing
In competitive industry, economical and environmentally friendly production techniques are essential. In this sense, cleaner and more sustainable machining techniques are the industry’s focus. In addition to green methods, effective parametric control is
Tahir Mehmood, Muhammad Shahid Khalil
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Preferences for Posttraumatic Osteoarthritis Prevention Strategies in Individuals With Anterior Cruciate Ligament Injury

Arthritis Care &Research, EarlyView.
Objective There is growing interest in evaluating new strategies to delay or prevent posttraumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury. Methods Participants with a history of
Kevin Kennedy, Lily Waddell, Adam Easterbrook, Jeffrey N. Katz, Cale Jacobs, Morgan Jones, Faith Selzer, Elena Losina, Liana Fraenkel, Nick Bansback   +9 more
wiley   +1 more source

Optimization of energy management in Malaysian microgrids using fuzzy logic-based EMS scheduling controller

Scientific Reports
The microgrid (MG) faces significant security issues due to the two-way power and information flow. Integrating an Energy Management System (EMS) to balance energy supply and demand in Malaysian microgrids, this study designs a Fuzzy Logic Controller ...
Mohammad Nur-E-Alam, Tarek Abedin, Nur Aini Samsudin, Jana Petrů, Abdulwasa Bakr Barnawi, Manzoore Elahi M. Soudagar, T. M. Yunus Khan, Muhammad Nasir Bashir, Mohammad Aminul Islam, Boon Kar Yap, Tiong Sieh Kiong   +10 more
doaj   +1 more source

An Investigation on the Effect of Mango Seed and Pongamia Oil-Based Cutting Fluids on Surface Morphology During Turning of AISI 304 Steel

Lubricants
In today’s industrial applications, cutting fluids have attained prime importance due to their all-round features, including increase of tool life by lubrication of the tool at the tool–workpiece interface.
Aneesh Mishra, Vineet Dubey, Deepak K. Prajapati, Usha Sharma, Siddharth Yadav, Anuj Kumar Sharma   +5 more
doaj   +1 more source