Latest Developments in Industrial Hybrid Machine Tools that Combine Additive and Subtractive Operations [PDF]
, 2018 Hybrid machine tools combining additive and subtractive processes have arisen as a solution to increasing manufacture requirements, boosting the potentials of both technologies, while compensating and minimizing their limitations.
Arrizubieta Arrate, Jon Iñaki +4 more
core +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Machines, 2023 Improving machining performance and meeting the requirements of sustainable production at the same time represents a major challenge for the metalworking industry and scientific community.
Luka Celent +3 more
doaj +1 more source
Fog computing and convolutional neural network enabled prognosis for machining process optimization [PDF]
, 2019 Cloud enabled prognosis systems have been increasingly adopted by manufacturing industries. The effectiveness of the cloud systems is, however, crippled by the high latency of data transfer between shop floors and the cloud.To overcome the limitation ...
Li, Weidong +3 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Eco-efficient process based on conventional machining as an alternative technology to chemical milling of aeronautical metal skin panels [PDF]
, 2019 El fresado químico es un proceso diseñado para la reducción de peso de pieles metálicas que, a pesar de los problemas medioambientales asociados, se utiliza en la industria aeronáutica desde los años 50.
Sol Illana, Irene del
core
A concept of water usage efficiency to support water reduction in manufacturing industry [PDF]
, 2016 Increasing pressures on freshwater supplies, continuity of supply uncertainties, and costs linked to legislative compliance, such as for wastewater treatment, are driving water use reduction up the agenda of manufacturing businesses.
Rahimifard, Shahin +2 more
core +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Optimization and analysis of cutting parameters using cryogenic media in machining of high strength alloy steel [PDF]
, 2013 In this research, liquid Argon is used as a cryogenic media to optimize the cutting parameters for evaluation of tool flank wear width of Tungsten Carbide Insert (CNMG 120404-WF 4215) while turning high strength alloy steel.
Ali, Liaqat +5 more
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source