Results 61 to 70 of about 4,579 (301)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Environmentally benign machining

This book provides essential information on environmentally benign/sustainable machining processes including innovations and developments in conventional machining, considering economy, safety, and productivity.
Bayraktar, Şenol, Pathak, Sunil
core   +1 more source

A Mathematical Model of the Cutting Force while Turning AISI 5140 Steel with P20 Carbide Inserts

Журнал інженерних наук
This article deals with the prediction of the main component of cutting force during turning operations. Currently, cutting force modeling is predominantly based on experimental data and is therefore largely empirical.
Stanislav Shvets, Vitalii Kolesnyk, Ivan Dehtiarov, Roman Shvets, Vladimír Šimna, Andrii Dovhopolov, Yurii Nekrasov, Bohdan Medvediev   +7 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Towards Smart and Competitive Sustainable Machining

, 2010
Computer Numeric Control (CNC) revolutionized the machining technology and has been the cutting edge of digital manufacturing since 1950s. CNC machining model, simulation, verification, and optimization have been a vivid research topic of Smart Machining
Pei Ling Liu
core   +1 more source

Evaluation of Cutting Forces and Temperatures in Micro-Milling of NiTi Alloys Using Finite Element Modeling

Журнал інженерних наук
Today, micro-milling of NiTi alloys is used to manufacture precision mechanisms, instrumentation, space technology, micro-electro-mechanical systems, biomedical devices, and implants. It is becoming increasingly widespread.
Nataliia Balytska, Oleh Tomashevskyi, Valentina Shadura   +2 more
doaj   +1 more source

Causal machine learning for sustainable agroecosystems

CoRR
In a changing climate, sustainable agriculture is essential for food security and environmental health. However, it is challenging to understand the complex interactions among its biophysical, social, and economic components. Predictive machine learning (ML), with its capacity to learn from data, is leveraged in sustainable agriculture for applications
Vasileios Sitokonstantinou, Emiliano Díaz Salas Porras, Jordi Cerdà-Bautista, Maria Piles, Ioannis Athanasiadis 0001, Hannah Kerner, Giulia Martini, Lily-belle Sweet, Ilias Tsoumas, Jakob Zscheischler, Gustau Camps-Valls   +10 more
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Enhancement of Machining Performance of Ti-6Al-4V Alloy Though Nanoparticle-Based Minimum Quantity Lubrication: Insights into Surface Roughness, Material Removal Rate, Temperature, and Tool Wear

Journal of Manufacturing and Materials Processing
In competitive industry, economical and environmentally friendly production techniques are essential. In this sense, cleaner and more sustainable machining techniques are the industry’s focus. In addition to green methods, effective parametric control is
Tahir Mehmood, Muhammad Shahid Khalil
doaj   +1 more source