Results 91 to 100 of about 623,411 (305)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Scientific ReportsThe growing expansion of the manufacturing sector, particularly in Mexico, has revealed a spectrum of nearshoring opportunities yet is paralleled by a discernible void in educational tools for various stakeholders, such as engineers, students, and ...
Pedro Ponce +6 more
doaj +1 more source
Understanding environmental performance variation in manufacturing companies [PDF]
, 2013 Sustainability is an area of increasing interest for industry and its stakeholders, and some companies now aspire to address sustainability issues (e.g. carbon emissions) at strategic and operational levels.
Bocken, Nancy +2 more
core +2 more sources
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
A Computer Vision Approach for Performance Tracking of Robotic Compliant Systems
Engineering ReportsCharacterization and testing of 3D‐printed robotic compliant systems for lifespan assessment is time‐consuming and costly. For this reason, this work introduces a computer vision approach for automated, non‐invasive monitoring of grippers and evaluation ...
E. Morales‐Vargas +3 more
doaj +1 more source
International Journal of Sustainable EngineeringWe introduce the innovative concept of Sustainable Laser Energy Consumption (SLEC, ε) that promotes sustainable metal additive manufacturing practices while maintaining productivity and tailored densification in the Selective Laser Melting (SLM) process.
Jorge A. Estrada-Díaz +6 more
doaj +1 more source
An innovation-focused roadmap for a sustainable global photovoltaic industry [PDF]
, 2014 The solar photovoltaic (PV) industry has undergone a dramatic evolution over the past decade, growing at an average rate of 48 percent per year to a global market size of 31. GW in 2012, and with the price of crystalline-silicon PV module as low as $0.72/
Kammen, DM, Zheng, C
core +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Wearable TechnologiesThis paper explores the integration of haptic gloves and virtual reality (VR) environments to enhance industrial training and operational efficiency within the framework of Industry 4.0 and Industry 5.0.
Mario Rojas +4 more
doaj +1 more source