Results 81 to 90 of about 5,278,876 (305)

Natural Language Processing (NLP)-Based Frameworks for Cyber Threat Intelligence and Early Prediction of Cyberattacks in Industry 4.0: A Systematic Literature Review

Applied Sciences
This study provides a systematic overview of Natural Language Processing (NLP)-based frameworks for Cyber Threat Intelligence (CTI) and the early prediction of cyberattacks in Industry 4.0. As digital transformation accelerates through the integration of
Majed Albarrak, Konstantinos Salonitis, Sandeep Jagtap   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

From failure to success: a framework for successful deployment of Industry 4.0 principles in the aerospace industry [PDF]

International Journal of Industrial Engineering and Operations Management
Purpose – The paper proposes a framework for the successful deployment of Industry 4.0 (I4.0) principles in the aerospace industry, based on identified success factors.
Sumit Gupta, Deepika Joshi, Sandeep Jagtap, Hana Trollman, Yousef Haddad, Yagmur Atescan Yuksek, Konstantinos Salonitis, Rakesh Raut, Balkrishna Narkhede   +8 more
doaj   +1 more source

Sustainability Characterization for Additive Manufacturing

Journal of Research of the National Institute of Standards and Technology, 2014
Additive manufacturing (AM) has the potential to create geometrically complex parts that require a high degree of customization, using less material and producing less waste. Recent studies have shown that AM can be an economically viable option for use by the industry, yet there are some inherent challenges associated with AM for wider acceptance. The
Mani, Mahesh, Lyons, Kevin W, Gupta, SK
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Are Intelligent Manufacturing Systems Sustainable? [PDF]

, 2014
This paper introduces and opens the debate on the place of "product-driven control" and, on a broader level, Intelligent Manufacturing and Services Systems in sustainable development and circular economy. First, IMS concept and perspectives on future industrial and economic systems, as well as their expected advantages and the challenges to be ...
Thomas, André, Trentesaux, Damien
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Assessment of the capability of an optical sensor for in-line real-time wastewater quality analysis in food manufacturing

Water Resources and Industry, 2018
This work investigates the use of a commercial optical product monitor to achieve in-line real-time water content analysis. Test fluids were used and optical measurements of attenuation of light intensity at four colours were made.
George Skouteris, D. Patrick Webb, Kei Lok Felix Shin, Shahin Rahimifard   +3 more
doaj   +1 more source

Towards Sustainability: The Manufacturers’ Perspective

, 2020
Moving towards more sustainable operations is a challenging goal for industries. The growth of interest in corporate sustainability performance has brought attention to the importance of accounting and transparency across economic, environmental and social dimensions.
Olena Klymenko, Lise Lillebrygfjeld Halse, Bjørn Jæger   +2 more
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source