Results 61 to 70 of about 5,278,876 (305)

Developing a Supportive Organisational Culture for Continuous Improvement in Manufacturing Firms in Saudi Arabia

Administrative Sciences
Continuous improvement (CI) is vital for Saudi manufacturing firms to remain competitive in the global market. However, cultural factors significantly influence CI adoption.
Adel Algethami, Fadi Assad, John Patsavellas, Konstantinos Salonitis   +3 more
doaj   +1 more source

Recent developments in bio-based polyethylene: Degradation studies, waste management and recycling

Heliyon, 2023
Nowadays, the tendency to replace conventional fossil-based plastics is increasing considerably; there is a growing trend towards alternatives that involve the development of plastic materials derived from renewable sources, which are compostable and ...
Manuel Burelo, Josué David Hernández-Varela, Dora I. Medina, Cecilia D. Treviño-Quintanilla   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Development of Hot Equal Channel Angular Processing (ECAP) Consolidation Technique in the Production of Boron Carbide(B4C)-Reinforced Aluminium Chip (AA6061)-Based Composite

International Journal of Renewable Energy Development, 2021
The production of metal matrix composites (MMCs) through recycled materials is a cost-saving process. However, the improvement of the mechanical and physical properties is another challenge to be concerned. In this study, recycled aluminium 6061 (AA6061)
Sami Al-Alimi, Mohd Amri Lajis, Shazarel Shamsudin, Nur Kamilah Yusuf, Boon Loong Chan, Djamal Hissein Didane, Mohammed H. Rady, Huda M. Sabbar, Munthader S. Msebawi   +8 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Uncertain programming model for designing multi-objective reverse logistics networks

Cleaner Logistics and Supply Chain
Given the contradiction between the rapid growth of products and the modest recovery rate of end-of-life products, there is a pressing need to understand the societal significance of establishing a reverse logistics network for end-of-life products. This
Hanbing Xia, Zhiyuan Chen, Jelena Milisavljevic-Syed, Konstantinos Salonitis   +3 more
doaj   +1 more source

Sustainable Manufacturing Technologies: A Systematic Review of Latest Trends and Themes

Sustainability, 2021
Meeting current needs while not sacrificing the future ability to do so as a key sustainability concept is becoming more challenging than ever, with the increasing population rate, energy poverty, global warming, and surging demand for products and ...
Ali Bastas
semanticscholar   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Microstructure and Mechanical Properties of Magnesium ZRE1 (Mg-Zn-Zr) Alloy with Rare Earth Element (Samarium) Addition

International Journal of Technology
The influences of rare earth (RE) samarium (Sm) added contents to ZRE1 (Mg-Zn-Zr) magnesium (Mg) cast alloy over strength properties to be investigated.
Ikhwan Shah Tisadi Tukiat, Nur Kamilah Yusuf, Haikal Khaireez, Sami Al-Alimi, Mohd Amri Lajis, Shazarel Shamsudin, Nasha Emieza Ruhaizat   +6 more
doaj   +1 more source