Results 71 to 80 of about 212,772 (313)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Unpacking Sustainable Packaging Through the Stimulus-Organism-Response Model: A Systematic Literature Review

SAGE Open
This study aims to synthesize key elements from sustainable packaging research on consumer behavior and apply the Stimulus-Organism-Response (SOR) model to understand consumer responses.
Aslıhan Kıymalıoğlu, Raife Meltem Yetkiän Özbük, Duygu Aydın Ünal, Onur Dirlik, Nuray Akar   +4 more
doaj   +1 more source

The conditions for implementing a circular economy in the Czech Republic [PDF]

, 2019
In July 2018, measures of the European Commission regarding the Circular Economy Package (CEP) came into force. All EU Member States have two years since to implement these measures into their national legislations.
Bařinka, Karel, Foltan, Drahomír, Grosoš, Roland, Janovská, Kamila, Piecha, Marian, Podlasová, Anežka, Vilamová, Šárka, Šanda, Martin, Šikýř, Petr   +8 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Sector-specific corporate responsibility in the United Kingdom [PDF]

, 2013
The economy of the United Kingdom (UK) is dominated by services and particularly financial services industries, and it was thus hard hit by the financial crisis.
Schaefer, Anja
core  

A Consumer-Centric Open Innovation Framework for Food and Packaging Manufacturing [PDF]

, 2015
This article has been archived following written permission from IGI Global.Closed innovation approaches have been employed for many years in the food industry.
Baurley, S, Ceschin, F, Green, S, Makatsoris, C, Qin, SF, Rodden, T, Song, J, Tsimiklis, P   +7 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Making the rich richer? Value distribution in the conventional, organic and fair trade banana chains of the Dominican Republic [PDF]

, 2008
On assiste aujourd'hui à l'essor de certifications privées permettant de différencier les produits auprès des consommateurs. De nombreuses certifications mettent ainsi en avant le respect de l'environnement et l'équité.
Lescot, Thierry, Loeillet, Denis, Roquigny, Solveig, Vagneron, Isabelle   +3 more
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