Results 101 to 110 of about 294,802 (264)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Impact of Environmental Tax on Corporate Sustainable Performance: Insights from High-Tech Firms in China. [PDF]

Int J Environ Res Public Health, 2022
Zhao X, Li J, Li Y.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Green Human Resource Management On Sustainable Performance: The Mediating Role Of Digital Innovation

Iqtishaduna: Jurnal Ilmiah Ekonomi Kita
This study analyses the mediating role of digital innovation variables on the relationship between green human resource management (GHRM) and sustainability performance.
Rudy Tobing, Dwiyanjana Santyo Nugroho
doaj   +1 more source

Green Management and Sustainable Performance of Small- and Medium-Sized Hospitality Businesses: Moderating the Role of an Employee's Pro-Environmental Behaviour. [PDF]

Int J Environ Res Public Health, 2023
Elshaer IA, Azazz AMS, Fayyad S.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Environmental regulations in eco-innovation and sustainable performance in Mexican Automotive Industry

La Granja: Revista de Ciencias de la Vida
In the literature, evidence has been provided that establishes that compliance with environmental regulations promotes the adoption and implementation of eco-innovation activities in manufacturing firms, since through this type of activities not only ...
Gonzalo Maldonado-Guzmán, Víctor Manuel Molina-Morejón, Raymundo Juárez del Toro   +2 more
doaj  

Assessing the impact of environmental, occupational health and safety, and food safety management systems on the sustainable performance of food processing companies

Frontiers in Sustainable Food Systems
The contemporary business environment places significant emphasis on sustainability, safety, and quality, particularly within the food processing industry.
Naveed Hayat, Ghulam Mustafa, Muhammad Naeem, Bader Alhafi Alotaibi, Abou Traore   +4 more
doaj   +1 more source

Determinants of cloud computing integration and its impact on sustainable performance in SMEs: An empirical investigation using the SEM-ANN approach. [PDF]

Heliyon, 2023
Al-Sharafi MA, Iranmanesh M, Al-Emran M, Alzahrani AI, Herzallah F, Jamil N.   +5 more
europepmc   +1 more source