Results 91 to 100 of about 294,802 (264)

Exploring the moderating effect of social intelligence on the relationship between entrepreneurial decision-making strategy and SME sustainable performance

MATEC Web of Conferences, 2018
The study reveals that causation, rather than effectuation, decision-making strategy is a more significant predictor of sustainable performance of SMEs. However, social intelligence was not found to be a significant moderator of entrepreneurial decision ...
Muhd Yusuf Dayang Hasliza, Hj. Din Mohd Salleh, Jusoh Muhamad Shahar   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Collaboration for Innovation and Sustainable Performance: Evidence of Relationship in Electro-Electronic Industry

BBR: Brazilian Business Review, 2016
This study aimed to identify how collaboration for innovation relates to the sustainable performance of the electronics industry in Brazil. We used a quantitative approach, collecting data by means of a cross-sectional survey in a sample of 112 companies.
Marcos Roberto Kuhl, João Carlos da Cunha, Marlete Beatriz Maçaneiro, Sieglinde Kindl da Cunha   +3 more
doaj  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Experimental Evaluation of Most Sustainable Companies: Impact on Economic Growth, Return on Equity (ROE) and Methodological Comparison

Economics and Culture
The study aims to analyse, how the sustainable performance of the company impacts the economy and businesses' economic performance, and to build a model, using environmental, social, and financial indicators.
Serzante Milena, Stankevych Viktoriia
doaj   +1 more source

Determinant of Sustainability Performance

Journal of Applied Accounting and Taxation
This study examines whether diversification impacts good corporate governance proxied by the board of directors, independent commissioners, audit committees, institutional ownership, and intellectual capital on sustainability performance. This research explores previous studies regarding sustainability performance.
Asih Handayani, Ratih Qadarti Anjilni
openaire   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

The Advantages of Entrepreneurial Holism: A Possible Path to Better and More Sustainable Performance

Administrative Sciences
In the present business environment, the strategic challenge of increasing performance along multiple dimensions simultaneously—e.g., financial, social, and personal—has never been greater.
Richard J. Arend
doaj   +1 more source