Results 81 to 90 of about 1,875,687 (306)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Towards a greener tomorrow: investigating the nexus of GHRM, technology innovation, and employee green behavior in driving sustainable performance

Cogent Business & Management
In response to the global imperative to address climate change, organizations are increasingly pressured to reduce industrial waste, curb carbon emissions, and adopt environmentally responsible practices.
Muhammad Shoaib, Nosheen Qadeer, Roman Zámečník, Mohsin Javed, Ayesha Nawal   +4 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

THE EFFECT OF GREEN SUPPLY CHAIN MANAGEMENT AND COMPETITIVE ADVANTAGES ON SUSTAINABLE PERFORMANCE OF INDONESIAN SMEs [PDF]

This research was carried out in Malang, Indonesia, focusing on Small and Medium- sized Enterprises (SMEs) and involving a sample of 100 participants.
Hakimi, Abdul Qadir
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The Relationship Between Interprofessional Team Collaboration and Sustainable Performance Among Healthcare Workers: A Public Hospital Case

Sağlık ve Hemşirelik Yönetimi Dergisi
Aim: Healthcare institutions are inherently competitive environments. In a competitive environment, disciplines must protect their own areas while also requiring inclusive teamwork. In addition, since the performance of healthcare workers is reflected in
Keziban Avcı, Yasin Aras
doaj   +1 more source

ASSESSING PERFORMANCE OF THE SUSTAINABLE SPATIAL DEVELOPMENT: ROMANIAN CASE STUDY [PDF]

The sustainable development requires to be implementing on the efficiencyprinciples of the sustainable development, which has to be appreciated depending on abenchmark system.
Vasile Burja
core  

How to achieve sustainability : regulatory challenges [PDF]

, 2005
The importance of designing sustainable buildings is gaining greater acceptance worldwide. Evidence of this is how regulators are incorporating sustainable design principles into building regulations and requirements.
Ambrose, Michael, Miller, Anne
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source