Results 71 to 80 of about 10,577,795 (233)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Sustainable development and UK faith groups : two sides of the same coin? : a survey of UK faith communities’ sustainable development activities and next steps for the future [PDF]

open access: yes, 2012
English language version of 'Datblygu cynaliadwy a grwpiau ffydd y DU : dwy ochr yr un geiniog? : arolwg o weithgareddau datblygu cynaliadwy cymunedau ffydd y DU a’r camau nesaf ar gyfer y dyfodol'.A survey of UK faith communities’ sustainable ...
World Wildlife Fund UK   +1 more
core   +2 more sources

The Relationship Between Interprofessional Team Collaboration and Sustainable Performance Among Healthcare Workers: A Public Hospital Case

open access: yesSağlık ve Hemşirelik Yönetimi Dergisi
Aim: Healthcare institutions are inherently competitive environments. In a competitive environment, disciplines must protect their own areas while also requiring inclusive teamwork. In addition, since the performance of healthcare workers is reflected in
Keziban Avcı, Yasin Aras
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Comprehensive area assessment consultation [PDF]

open access: yes, 2012
The proposals for the new comprehensive area assessment are a very positive step forward for sustainable development compared to previous local performance assessment frameworks, but will need further strengthening if they are to help support the ...
Sustainable Development Commission
core   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

A Business Model to Support Sustainable Performance of Digital Startup Companies

open access: yesCSID Journal of Infrastructure Development, 2019

Pri Agung Danarahmanto, Yudi Azis
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Sustainable development : the key to tackling health inequalities [PDF]

open access: yes, 2012
In November 2008, Professor Sir Michael Marmot was asked to advise the Secretary of State for Health on the future development of a health inequalities strategy in England post-2010.
Sustainable Development Commission
core   +2 more sources

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