Results 51 to 60 of about 3,236,046 (302)
There is much uncertainty over whether on-demand ridehailing services, namely Uber and Lyft, will worsen or alleviate existing transportation problems such as congestion, emissions, and inequities in access and mobility.
National Center for Sustainable Transportation (NCST) +2 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Intergovermental Cooperation Initiative on Sustainable Transportation Management in Jabodetabek
The main issues in Jabodetabek concerning the management of transportation are related to the increased use of private vehicles and the decreased use of public transportation, overcrowding daily traffic in Jabodetabek, the high congestion followed by ...
Hidayat Chusnul Chotimah
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Recently, automation, shared use, and electrification are viewed as the “three revolutions” in the future transportation sector, and the traditional scheduled public transit system will be greatly enhanced with flexible services and autonomous vehicle ...
Xuesong Zhou +8 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Sustainable Transportation Curricula [PDF]
The National Center for Sustainable Transportation (NCST) seeks to ensure that transportation professionals have the necessary knowledge and skills to design, operate, and maintain sustainable transportation systems.
Guensler, Randall +7 more
core
Setting Transportation Network Company Policies to Increase Sustainability [Policy Brief]
Use of Transportation Network Companies (TNCs) such as Uber and Lyft has grown rapidly in cities across the United States. TNCs often provide a cheaper and more flexible travel option than traditional taxi services, and could improve transportation ...
Kunz, Tatjana +5 more
core +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
A Funding Compromise Can Set Transportation on Path Towards Sustainability [Policy Brief] [PDF]
DTRT13-G-UTC29A number of proposals have sought to address aspects of securing or reforming state and federal transportation funding. This policy brief summarizes findings from a white paper that assembles the most prominent of these proposals and ...
National Center for Sustainable Transportation (NCST) +1 more
core

