Results 51 to 60 of about 123,234 (304)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Stakeholder Perspectives on the Sustainable Transportation Implications of On-demand Ridehailing [Policy Brief]

There is much uncertainty over whether on-demand ridehailing services, namely Uber and Lyft, will worsen or alleviate existing transportation problems such as congestion, emissions, and inequities in access and mobility.
National Center for Sustainable Transportation (NCST), Pike, Susan, University of California, Davis, Institute of Transportation Studies   +2 more
core   +1 more source

Open-source VRPLite Package for Vehicle Routing with Pickup and Delivery: A Path Finding Engine for Scheduled Transportation Systems

Urban Rail Transit, 2018
Recently, automation, shared use, and electrification are viewed as the “three revolutions” in the future transportation sector, and the traditional scheduled public transit system will be greatly enhanced with flexible services and autonomous vehicle ...
Xuesong Zhou, Lu Tong, Monirehalsadat Mahmoudi, Lijuan Zhuge, Yu Yao, Yongxiang Zhang, Pan Shang, Jiangtao Liu, Tie Shi   +8 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Steady-State Car-Following Time Gaps: An Empirical Study Using Naturalistic Driving Data

Journal of Advanced Transportation, 2019
The time gap is defined as the time difference between the rear of a vehicle and the front of its follower, which affects both safety and the saturation flow rate of a roadway segment.
Amara Loulizi, Youssef Bichiou, Hesham Rakha   +2 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Sustainable Transportation Curricula [PDF]

The National Center for Sustainable Transportation (NCST) seeks to ensure that transportation professionals have the necessary knowledge and skills to design, operate, and maintain sustainable transportation systems.
Guensler, Randall, National Center for Sustainable Transportation (NCST), Georgia Institute of Technology. School of Civil and Environmental Engineering, Rodgers, Michael O., Cruz, Judith, Macfarlane, Gregory S, Xu, Yanzhi, University of California, Davis, Institute of Transportation Studies   +7 more
core  

Setting Transportation Network Company Policies to Increase Sustainability [Policy Brief]

Use of Transportation Network Companies (TNCs) such as Uber and Lyft has grown rapidly in cities across the United States. TNCs often provide a cheaper and more flexible travel option than traditional taxi services, and could improve transportation ...
Kunz, Tatjana, Brown, Austin L, National Center for Sustainable Transportation (NCST), D'Agostino, Mollie Cohen, Fuller, Sam, University of California, Davis, Institute of Transportation Studies   +5 more
core   +1 more source