Results 71 to 80 of about 123,234 (304)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Understanding the Bike-share Market in the Sacramento Region to Increase Demand and Improve Access [Policy Brief]

Bike-share services provide an affordable and environmentally sustainable transportation option. Research has shown that bike-share use can reduce car dependence and facilitate access to public transit. Expanding the use of these services can help cities
National Center for Sustainable Transportation (NCST), Mohiuddin, Hossain, Fitch, Dillon, Handy, Susan, University of California, Davis, Institute of Transportation Studies   +4 more
core   +1 more source

Mapping Water Quality Modelling and Catchment Management Research Trends for Sustainable Development in South Africa

Science, Engineering and Technology
Water quality degradation in river catchments remains one of the most critical environmental and infrastructural challenges facing South Africa, which mainly involves urbanisation, industrial activities, agricultural runoff, and climate variability. This
Nura Shehu Aliyu Yaro, Zesizwe Ngubane, Jacob Adedayo Adedeji   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Challenges and Opportunities for Integrating Climate Adaptation Efforts across State, Regional and Local Transportation Agencies [PDF]

To address the challenges posed by climate change to the transportation system, agencies are investigating climate change adaptation measures. This white paper presents a five-step framework for adapting transportation systems: inventorying and ...
University of Vermont. Transportation Research Center, National Center for Sustainable Transportation (NCST), Aultman-Hall, Lisa, Dowds, Jonathan   +3 more
core  

Developing a Vehicle Cost Calculator to Promote Electrical Vehicle Adoption Among Transportation Network Company (TNC) Drivers

USDOT Grant 69A3551747114National Transportation Library (NTL) Curation Note: This dataset is preserved in a repository outside U.S. DOT control, as allowed by the U.S.
National Center for Sustainable Transportation (NCST), Sanguinetti, Angela, University of California, Davis. Institute of Transportation Studies   +2 more
core   +1 more source

Southern California Transit Training Consortium Online Training in Electrical Systems and Battery Electric Safety Training [PDF]

USDOT Grant 69A3551747114In partnership with the Southern California Regional Transit Training Consortium (SCRTTC), the California State University at Long Beach (CSULB) expanded potential audiences and offered program support for the Electric Vehicle ...
National Center for Sustainable Transportation (NCST), California State University, Long Beach. Center for International Trade and Transportation, O'Brien, Thomas J   +2 more
core   +1 more source

Purchase subsidies for 100% zero-emissions vehicle sales goals: Effectiveness, government cost, and supplier capture

Transportation Research Interdisciplinary Perspectives
Globally, purchase subsidies are among the most common policies used to support the deployment of zero-emissions vehicles (ZEVs). However, it is unclear if subsidies alone can effectively and efficiently achieve ambitious long-term ZEV sales goals, such ...
Chandan Bhardwaj, Jonn Axsen
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Microscopic mechanism and predicting calculation on mechanical properties of basalt fiber modified 3D printing cement-based materials

Case Studies in Construction Materials
This study focuses on the modification and intelligent-digital control of 3D printing materials. Based on the significant effect of basalt fiber in improving toughness, the influence mechanism of basalt fiber substitution rate, length and other factors ...
Ben Li, Kaihang Li, Xuetao Lyu, Canhao Zhao, Xianzhang Guan   +4 more
doaj   +1 more source