Results 81 to 90 of about 123,234 (304)
Indonesian Journal of Geography, 2013 Sustainable transportation becomes very important in a certain town since it can influence the development of the town itself. One of the sustainable transportations is angkot (urban public transportation). Urban public transportation is one of the means
Hairulsyah .
doaj +1 more source
A New Method for Designing Dense Skeleton Asphalt Mixture Based on Meso Parameter
Advances in Civil Engineering, 2020 At present, research on the internal structures of asphalt mixtures has mostly focused on the statistical analysis of their mesostructural components such as aggregates, voids, and asphalt mortars, in addition to the verification of the mechanical ...
Liwan Shi +5 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
From LOS to VMT: Repurposing Impact Fee Programs Since Adoption of SB 743 [PDF]
Caltrans 65A0686 Task Order 049 USDOT Grant 69A3551747114This white paper assesses how cities are modifying transportation impact fees in response to Senate Bill (SB) 743, adopted in 2013 to orient environmental review of transportation impacts of ...
Barbour, Elisa +2 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Mode Share Changes in California: An Exploratory Analysis of Factors Affecting Decreases in Walking, Biking and Transit Use from 2012 to 2017 [PDF]
Caltrans 65A0686 Task Order 063 USDOT Grant 69A3551747114This study explores the factors associated with observed changes in transportation mode shares over the period from 2012 to 2017 (corresponding with the period between the two most recent household
National Center for Sustainable Transportation (NCST) +3 more
core +1 more source
The Baltic Journal of Road and Bridge EngineeringThe reasonable selection of soil layer parameters relates to the accurate prediction of the horizontal deformation of the foundation pit, which is the main problem of highway tunnel pit design.
Yu Zhang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source