Results 61 to 70 of about 3,236,046 (302)

Understanding the Bike-share Market in the Sacramento Region to Increase Demand and Improve Access [Policy Brief]

Bike-share services provide an affordable and environmentally sustainable transportation option. Research has shown that bike-share use can reduce car dependence and facilitate access to public transit. Expanding the use of these services can help cities
National Center for Sustainable Transportation (NCST), Mohiuddin, Hossain, Fitch, Dillon, Handy, Susan, University of California, Davis, Institute of Transportation Studies   +4 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Steady-State Car-Following Time Gaps: An Empirical Study Using Naturalistic Driving Data

Journal of Advanced Transportation, 2019
The time gap is defined as the time difference between the rear of a vehicle and the front of its follower, which affects both safety and the saturation flow rate of a roadway segment.
Amara Loulizi, Youssef Bichiou, Hesham Rakha   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Spatio-temporal dynamics along the terrain gradient of diverse landscape

Journal of Environmental Engineering and Landscape Management, 2014
Land use (LU) land cover (LC) information at a temporal scale illustrates the physical coverage of the Earth’s terrestrial surface according to its use and provides the intricate information for effective planning and management activities.  LULC changes
T. V. Ramachandra, Settur Bharath, Aithal Bharath   +2 more
doaj   +1 more source

A Funding Compromise Can Set Transportation on Path Towards Sustainability [PDF]

DTRT13-G-UTC29A number of proposals in the past year have sought to address aspects of securing or reforming state and federal transportation funding.
National Center for Sustainable Transportation (NCST), Niemeier, Deb, University of California, Davis, Institute of Transportation Studies   +2 more
core  

Expanded Workforce Development Opportunities are Needed for Transportation Sector Climate Adaptation Professionals [Policy Brief] [PDF]

Early investments in climate change research, policy, and planning focused heavily on climate mitigation\u2014efforts to reduce greenhouse gas emissions.
National Center for Sustainable Transportation (NCST), Dowds, Jonathan, McRae, Glenn, University of California, Davis, Institute of Transportation Studies   +3 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Southern California Transit Training Consortium Online Training in Electrical Systems and Battery Electric Safety Training [PDF]

USDOT Grant 69A3551747114In partnership with the Southern California Regional Transit Training Consortium (SCRTTC), the California State University at Long Beach (CSULB) expanded potential audiences and offered program support for the Electric Vehicle ...
National Center for Sustainable Transportation (NCST), California State University, Long Beach. Center for International Trade and Transportation, O'Brien, Thomas J   +2 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source