Results 71 to 80 of about 3,864,837 (295)

Oscillatory Dynamics in the Frontoparietal Attention Network during Sustained Attention in the Ferret

open access: yesCell Reports, 2016
Sustained attention requires the coordination of neural activity across multiple cortical areas in the frontoparietal network, in particular the prefrontal cortex (PFC) and posterior parietal cortex (PPC).
Kristin K. Sellers   +7 more
doaj   +1 more source

Connectome-based neurofeedback: A pilot study to improve sustained attention

open access: yesNeuroImage, 2020
Real-time functional magnetic resonance imaging (rt-fMRI) neurofeedback is a non-invasive, non-pharmacological therapeutic tool that may be useful for training behavior and alleviating clinical symptoms.
Dustin Scheinost   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Mindfulness training, spatial attention, and EEG

open access: yes, 2016
In this research project we examined whether an 8-week Mindfulness training induces measurable changes effects of spatial atention on the orienting towards and the processing of nocicpetive stimuli as measured with EEG and SDT measures.
Lubbe, Dr. R.H.J. van der (University of Twente), ProjectMember
core   +1 more source

Single and combined effects of sympathetic and parasympathetic activity on perceptual sensitivity and attention [PDF]

open access: yes, 1999
Pulse rate and cephalic pulse volume were recorded from 17 male and 37 female normal subjects during performance of an attentional task under high and low stress conditions.
Davydov, Dmitry M., Shapiro, David
core   +2 more sources

Mastication while rested does not improve sustained attention in healthy participants conducting short-duration cognitive tasks

open access: yesActa Psychologica
Sustained attention is important for optimal neurobehavioral performance, but many biological and environmental factors (e.g., circadian rhythm, distraction, etc.) may cause sustained attention deficits.It has been suggested that mastication (chewing ...
Devon A. Hansen   +2 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Attention and Neurocognitive Impairment in ADHD

open access: yesPediatric Neurology Briefs, 2007
Specific executive functions (EFs) and attention deficit patterns in ADHD subtypes were studied in 50 boys (ages 8-14 years, mean 10.42) with ADHD and 44 controls, at the University of Rome, Italy.
J Gordon Millichap
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy