Results 91 to 100 of about 351,668 (260)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Association Between EEG Microarousal During Nocturnal Sleep and Next-Day Selective Attention in Mild Sleep-Restricted Healthy Undergraduates

Nature and Science of Sleep
Diguo Zhai,1,2 Qingwei Chen,1,2 Ying Yao,3 Taotao Ru,1,2 Guofu Zhou1,2 1Guangdong Provincial Key Laboratory of Optical Information Materials and Technology, Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South ...
Zhai D, Chen Q, Yao Y, Ru T, Zhou G
doaj  

Length of Methamphetamine Abuse and Sustained Attention Disorders among Methamphetamine Abusers

Research on Addiction, 2013
Introduction: The aim of this study was to investigate relation between sustained attention disorders and lenght of Methamphetamine abuse. Method: 200 Methamphetamine abusers (males and females) of ages 20-40 who were recruited through residential ...
lyeli Siahjani, mohammad Oraki, hossein zare   +2 more
doaj  

Sustained attention in schizophrenia

, 2012
abstract ; toc ; published_or_final_version ; Clinical Psychology ; Master ; Master of Social ...
openaire   +2 more sources

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

The Effects of Neurofeedback, Yoga Interventions on Memory and Cognitive Activity in Children with Attention Deficit/Hyperactivity Disorder: A Randomized Controlled Trial

Annals of Applied Sport Science, 2018
Background. Neuro-feedback (NFB) and physical activities are considered alternative treatments for children with ADHD that aims to optimize brain activity. Assessments of the behavioral efficacy of NF and physical interventions have produced inconsistent
Meysam Rezaei, Tayebe Salarpor Kamarzard, Mahdi Najafian Razavi   +2 more
doaj  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

The study of sustained attention of children with attention deficit-hyperactivity disorder and typical children

مجله علوم روانشناختی, 2016
Attention Deficit and Hyperactivity Disorder (ADHD) is a neurodevelopmental and behavioral disorder. Dysfunction in executive functions is core symptom of ADHD. The aim of this study is to compare the sustained attention in children with ADHD and typical
Vahid Nejati, Fatemeh Abadi, Zahra Ramezannia, Asal Najian   +3 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Local and global contribution to selective and sustained attention

Current Research in Behavioral Sciences
This study introduces an innovative approach to measuring coherent motion thresholds under conditions that separately evaluate global and local visual contributions to sustained selective attention.
Victoria Geraldi Menegon, Natalia Máximo Alves Rocha, Leonardo Dutra Henriques, Marcelo Fernandes Costa   +3 more
doaj   +1 more source