Positive predictive value of sustained virologic response 4 weeks posttreatment for achieving sustained virologic response 12 weeks posttreatment in patients receiving glecaprevir/pibrentasvir in Phase 2 and 3 clinical trials. [PDF]
Sustained virologic response at posttreatment Week 12 (SVR12) is the widely accepted efficacy endpoint for direct‐acting antiviral agents. Those with hepatitis C virus (HCV) are presenting younger with milder liver disease, potentially reducing need for ...
Gane E+9 more
europepmc +2 more sources
Characteristics and Prognosis of De Novo Hepatocellular Carcinoma After Sustained Virologic Response. [PDF]
Hepatocellular carcinoma (HCC) can de novo develop in patients with chronic hepatitis C even after the achievement of sustained virologic response (SVR).
Toyoda H+22 more
europepmc +2 more sources
Nachbetreuung von PatientInnen mit „sustained virologic response“ [PDF]
Da die Therapie der chronischen Hepatitis C aufgrund der neuen direkt antiviral wirkenden Therapeutika („direct-acting antivirals“, DAA) aus virologischer Sicht bei nahezu allen PatientInnen zur nachhaltigen Ausheilung („sustained virologic response ...
G. Semmler, M. Mandorfer
semanticscholar +2 more sources
Frequency of Sustained Virologic Response in Hepatitis C Positive, Treatment Naïve Patients on Sofosbuvir and Daclatasvir [PDF]
OBJECTIVES To measure the frequency of sustained virologic response in Hepatitis C positive, treatment naïve patients on Sofosbuvir and Daclatasvir.
Islam Shah+3 more
doaj +3 more sources
Treatment predictors of a sustained virologic response in hepatitis B and C [PDF]
Treatment predictors are important tools for the management of therapy in patients with chronic hepatitis B and C virus (HBV, HCV) infection. In chronic hepatitis B, several pretreatment parameters have been identified for prediction of virologic response to interferon alfa-based antiviral therapies or treatment with polymerase inhibitors.
Annika Kau+2 more
openalex +5 more sources
Durability of Sustained Virologic Response in Chronic Hepatitis C [PDF]
Background/AimsThe aim of this study is to investigate the rate of sustained virologic response (SVR) in chronic hepatitis C patients receiving antiviral treatment.Methods : The files of patients with chronic hepatitis C treated with interferon±ribavirin
Ahmet Danalioglu+8 more
doaj +5 more sources
Achieving the Sustained Virologic Response With a Short-Course Treatment of Sofosbuvir/Velpatasvir. [PDF]
Hepatitis C, a single-stranded RNA virus officially discovered in 1989, is one of the most known viruses of the Flaviviridae family. Direct-acting antiviral drugs helped revolutionize the management of hepatitis C infection by guaranteeing higher cure rates.
Abi-Saleh SP, Ghazal F, Urtasun Sotil E.
europepmc +3 more sources
Development and surveillance of hepatocellular carcinoma in patients with sustained virologic response after antiviral therapy for chronic hepatitis C [PDF]
Hepatitis C virus (HCV) infection is a major risk factor for liver cirrhosis and hepatocellular carcinoma (HCC), and is a leading cause of liver-related deaths worldwide. Recently available direct-acting antiviral agent is very safe and highly effective (
Seong Kyun Na, Byung-Cheol Song
doaj +2 more sources
The sustained virologic response of nonresponder hepatitis C virus patients with retreatment
Background: Pegylated interferon and ribavirin combination therapy remain the first-line treatment for chronic hepatitis C virus (HCV) infection. In contrast to the large number of studies in treatment-naive patients, the effectiveness of retreatment in ...
Sila Cetin Akhan+2 more
doaj +5 more sources
Effect of sustained virologic response on the incidence of hepatocellular carcinoma in patients with HCV cirrhosis [PDF]
Background and objectives: Evidence suggests that sustained virologic response to interferon treatment decreases incidence of hepatocellular carcinoma in patients with hepatitis C virus cirrhosis.
Nelson Cheinquer+3 more
doaj +8 more sources