Alcohol Use and Sustained Virologic Response to Hepatitis C Virus Direct-Acting Antiviral Therapy.
Key Points Question Is alcohol use associated with achieving a sustained virologic response (SVR) when treating hepatitis C virus (HCV) infection with direct-acting antiviral (DAA) therapy?
Cartwright EJ +10 more
europepmc +2 more sources
Positive predictive value of sustained virologic response 4 weeks posttreatment for achieving sustained virologic response 12 weeks posttreatment in patients receiving glecaprevir/pibrentasvir in Phase 2 and 3 clinical trials. [PDF]
Sustained virologic response at posttreatment Week 12 (SVR12) is the widely accepted efficacy endpoint for direct‐acting antiviral agents. Those with hepatitis C virus (HCV) are presenting younger with milder liver disease, potentially reducing need for ...
Gane E +9 more
europepmc +2 more sources
Characteristics and Prognosis of De Novo Hepatocellular Carcinoma After Sustained Virologic Response. [PDF]
Hepatocellular carcinoma (HCC) can de novo develop in patients with chronic hepatitis C even after the achievement of sustained virologic response (SVR).
Toyoda H +22 more
europepmc +2 more sources
Development and surveillance of hepatocellular carcinoma in patients with sustained virologic response after antiviral therapy for chronic hepatitis C [PDF]
Hepatitis C virus (HCV) infection is a major risk factor for liver cirrhosis and hepatocellular carcinoma (HCC), and is a leading cause of liver-related deaths worldwide. Recently available direct-acting antiviral agent is very safe and highly effective (
Seong Kyun Na, Byung-Cheol Song
doaj +2 more sources
Modern pharmacotherapy of chronic hepatitis C in patients who failed to achieve sustained virologic response [PDF]
Introduction. According to WHO experts, about 150 million people suffer from chronic viral hepatitis C (CHC), and 350,000 die annually as a result of liver damage by the hepatitis C virus (HCV).
Kireyev, I.V., Zhabotynska, N.V.
doaj +3 more sources
Background and objectives: Evidence suggests that sustained virologic response to interferon treatment decreases incidence of hepatocellular carcinoma in patients with hepatitis C virus cirrhosis.
Nelson Cheinquer +3 more
doaj +2 more sources
High sustained virologic response rates, regardless of race or socioeconomic class, in patients treated with chronic hepatitis C in community practice using a specialized pharmacy team. [PDF]
Kuwelker S +21 more
europepmc +2 more sources
ABT-450, Ritonavir, Ombitasvir, and Dasabuvir Achieves 97% and 100% Sustained Virologic Response With or Without Ribavirin in Treatment-Experienced Patients With HCV Genotype 1b Infection [PDF]
BACKGROUND & AIMS The interferon-free regimen of ABT-450 (a protease inhibitor), ritonavir, ombitasvir (an NS5A inhibitor), dasabuvir (a non-nucleoside polymerase inhibitor), and ribavirin has shown efficacy in patients with hepatitis C virus (HCV ...
Pietro Andreoné +13 more
openalex +2 more sources
Augmentation of hepatitis C virus‐specific immunity and sustained virologic response [PDF]
Shikha Shrivastava +6 more
openalex +2 more sources
Hepatitis C reinfection in patients with sustained virologic response at a national hospital in Peru, 2024. [PDF]
Zambrano-Huailla R +4 more
europepmc +3 more sources

