Results 161 to 170 of about 58,557 (260)

Liver fibrosis post SVR

open access: yes
Hepatitis C (HCV) recurrence after liver transplantation (LT) is universal if HCV-RNA persists at time of LT and progression to fibrosis can occur rapidly. Nowadays, sustained virological response (SVR) is obtained in 97% of HCV-infected patients treated
Dahlqvist, Géraldine   +1 more
core  

The Influence of Parenting Style on Neurocognitive Development of Children With an Extra X or Y Chromosome: A Prospective 1‐Year Follow‐Up Study

open access: yesAndrology, EarlyView.
ABSTRACT Background As sex chromosome trisomies (SCTs), including 47, XXX, 47, XXY, and 47, XYY, are associated with increased risk for neurodevelopmental challenges, studying SCTs may help in understanding the role of early parental caregiving in shaping neurodevelopmental phenotypes of this genetically at‐risk population.
Sophie van Rijn   +4 more
wiley   +1 more source

Integrating novel therapeutic strategies in myeloproliferative neoplasms: Driving disease‐directed progress

open access: yesBritish Journal of Haematology, EarlyView.
Summary Over the past decade, there has been a substantial increase in the diversity and number of therapeutic options for myeloproliferative neoplasms (MPNs). While many remain within the clinical trial arena, the clinician and patient community have seen more approvals reaching the clinic and a rethink on how best we should be approaching these ...
Trung Q. Ngo   +3 more
wiley   +1 more source

Janus kinase inhibitors after ruxolitinib failure in myelofibrosis: A systematic review and pooled analysis of phase 3 efficacy and integrated safety across clinical trials and real‐world evidence

open access: yesBritish Journal of Haematology, EarlyView.
Summary Ruxolitinib remains first‐line standard of care for symptomatic myelofibrosis, but resistance/intolerance develops in most patients. Three Janus kinase inhibitors (JAKis) have entered the post‐ruxolitinib space via distinct pivotal trials. We systematically searched prospective trials evaluating JAKi in refractory adults with myelofibrosis ...
Andrea Duminuco   +8 more
wiley   +1 more source

Tissue Factor‐High Ovarian Clear Cell Carcinoma Shows Immune‐Cold Features and Preclinical Activity of Tisotumab Vedotin

open access: yesCancer Science, EarlyView.
F3/TF‐high ovarian clear cell carcinoma exhibits an immune‐cold phenotype characterized by reduced immune‐cell fractions and attenuated cancer‐cell interferon programs, with frequent B7‐H4 co‐expression. Patient‐derived models show preclinical sensitivity to the TF‐directed antibody–drug conjugate tisotumab vedotin.
Yutaro Mori   +7 more
wiley   +1 more source

Navigating the Activist Techno‐Social Landscape: Washington, DC High School Students' Engagement with Social Media Content

open access: yesChildren &Society, EarlyView.
ABSTRACT In recent decades, youth activism has experienced a global resurgence, playing a pivotal role in advocating for social and political change across diverse national and international contexts. Drawing on empirical data from a study of high school students in diverse Washington, DC public schools, this paper offers a unique perspective on youth ...
Vanessa R. Sperduti   +3 more
wiley   +1 more source

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