Paediatric Solid Oral Dosage Forms for Combination Products: Improving In Vitro Swallowability of Minitablets Using Binary Mixtures with Pellets [PDF]
, 2023 There is a growing interest in determining and improving the acceptability of solid oral dosage forms (SODF) in paediatric populations. Combination products can be an interesting solution to combine two active pharmaceutical ingredients. This study shows
Kuehl, Peter +6 more
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A novel soft robotic pediatric in vitro swallowing device to gain insights into the swallowability of mini-tablets [PDF]
, 2022 International audienceSoft robotics could help providing a better understanding of the mechanisms underpinning the swallowability of solid oral dosage forms (SODF), especially by vulnerable populations such as the elderly or children.
Lavoisier, Anais +6 more
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Studying in vitro the swallowability of pediatric formulations using a novel soft robotic device [PDF]
, 2022 International audienceINTRODUCTIONMulti-particulate flexible solid oral dosage forms for pediatric present potentially several advantages over tradition solid oral dosage forms (SODF) or suspensions.
Kuehl, Peter +6 more
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Assessment of swallowability and palatability of oral dosage forms in children: Report from an M-CERSI pediatric formulation workshop [PDF]
, 2018 The acceptability of pediatric pharmaceutical products to patients and their caregivers can have a profound impact on the resulting therapeutic outcome.
Ternik, Robert +19 more
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Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1986 ABSTRACT:Swallow syncope is an often misdiagnosed rare disorder due to enhanced vagal tone during eating in patients with underlying esophageal and/or cardiac abnormalities. We present three cases of this disorder, one related to digitalis toxicity and the other two with diffuse esophageal spasm. The investigation, differential diagnosis, prognosis and
A, Guberman, J, Catching
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Swallowing in Conversation [PDF]
Frontiers in Communication, 2021 Swallowing—a complex physical process that involves closure of the mouth and nasal cavities, as well as the glottis, and the raising and lowering of the larynx—is at the boundary between speech and the body, yet almost nothing is known about how it works in conjunction with speech in spoken interaction.
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Pharmaceutics, 2022 Prednisolone is a frequently prescribed steroid with a bitter, unpalatable taste that can result in treatment refusal. Oral suspensions or powder dosage forms are often prescribed, particularly to pediatric patients, as they improve swallowability and ...
Mengyan Deng +7 more
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A review on taste masked multiparticulate dosage forms for paediatric for tenacity and toughness improvement [PDF]
, 2023 Taste refers to those sensations perceived through taste buds on the tongue and oral cavity. The unpleasant taste of drugs leads to the refusal of taking the medicine in the paediatric population.
AL-japairai, Khater Ahmed Saeed +7 more
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The application of tribology in assessing texture perception of oral liquid medicine [PDF]
, 2015 The palatability of medicines is likely to have a significant impact on patient adherence and consequently, on the safety and efficacy of a medicinal product. Palatability encompasses properties of medicines not limited to taste including swallowability (
Venables, Venables, RH
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