Results 91 to 100 of about 65,552 (266)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Controlling a Swarm of Low-Cost Underwater Vehicles Under Conditions of Limited Navigation, Communication and Observation

Sensors
This paper addresses the problem of controlling autonomous underwater vehicles (AUVs) operating in a swarm under realistic underwater conditions characterised by inaccurate navigation, limited acoustic communication, and noisy sonar observations. A novel
Tomasz Praczyk, Leszek Pietrukaniec, Maksymilian Wrzesień, Maciej Szymkowiak, Jakub Stalica   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Observation of the Preparation Phase Associated with Mw = 7.2 Haiti Earthquake on 14 August 2021 from a Geophysical Data Point of View

Geosciences
On 14 August 2021, an earthquake of moment magnitude Mw = 7.2 hit Haiti Island. Unfortunately, it caused several victims and economic damage to the island.
Dedalo Marchetti
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Formation Flight of Fixed-Wing UAVs: Dynamic Modeling, Guidance Design, and Testing in Realistic Scenarios

Aerospace
Autonomous unmanned flight based on fixed-wing aircraft constitutes a practical and economical solution for transport missions to remote destinations or disadvantaged communities, for which their payload and range represent interesting figures of merit ...
Carlo E.D. Riboldi, Marco Tomasoni
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Control of Multiple Underwater Vessels to Converge to a Desired Pattern

International Journal of Maritime Technology, 2018
The important and hazardous of the rescue mission in oceans and seas, autonomous vessels now are one of the most appropriate applications among others. Due to safety, reliability, and accessibility of smart, Autonomous and Cooperative vessels today has ...
Hassan Sayyaadi, Abbas Ghassemzadeh
doaj  

A Novel Technique for Extracting the Tidal Magnetic Field: Methodology and Application to a Pre‐Processed Dataset of CSES and Swarm

Geophysical Research Letters
The oceanic tidal magnetic field, mainly driven by the circular orbital motion of the Moon, is an essential part of the time‐varying geomagnetic field. The previously adopted time‐harmonic (TH) base worked well in fitting the primary M2 tidal field, but ...
Haoren Ma, Yanyan Yang, Zhaojin Rong, Dongquan Wang, Jiawei Gao, Zeren Zhima, Jie Wang, Bin Zhou, Werner Magnes, Fei He, Y. Wei   +10 more
doaj   +1 more source