Results 81 to 90 of about 64,835 (219)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Accurate modeling of Earth’s ionospheric F-region currents is essential for refining geomagnetic field models and understanding magnetosphere-ionosphere coupling.
JuYuan Xu, HongBo Yao, Keke Zhang
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Control of Multiple Underwater Vessels to Converge to a Desired Pattern
The important and hazardous of the rescue mission in oceans and seas, autonomous vessels now are one of the most appropriate applications among others. Due to safety, reliability, and accessibility of smart, Autonomous and Cooperative vessels today has ...
Hassan Sayyaadi, Abbas Ghassemzadeh
doaj
The oceanic tidal magnetic field, mainly driven by the circular orbital motion of the Moon, is an essential part of the time‐varying geomagnetic field. The previously adopted time‐harmonic (TH) base worked well in fitting the primary M2 tidal field, but ...
Haoren Ma +10 more
doaj +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Background. Unmanned aerial vehicles are currently actively used in the military, civil and scientific spheres of activity. Due to the use of the swarm, there are opportunities to increase the efficiency of the use of unmanned aerial vehicles.
Andrey P. Preobrazhenskiy +2 more
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

