Results 141 to 150 of about 16,275 (241)

Piezo1 Activation Rescues Anabolic Response to Mechanical Loading in Aged Bone via Connexin 43 Hemichannels

open access: yesAging Cell, Volume 25, Issue 9, September 2026.
Yoda1‐induced Piezo1 activation enhances Piezo1‐Cx43 interaction upon mechanical stimulation, triggering PI3K‐Akt signaling to drive Cx43 phosphorylation and hemichannel opening. These events elevate PGE2 release, suppress SOST expression in senescent osteocytes, and ultimately enhance bone anabolism on the endosteal surface.
Dezhi Zhao   +10 more
wiley   +1 more source

An attempt to improve recognition of fetal acidemia by a remodeled intrapartum cardiotocography classification: A case–control study

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 9, Page 1749-1760, September 2026.
Current CTG interpretation templates have shown low sensitivity or low specificity identifying fetuses with acidemia. This new interpretation template combined a high sensitivity with a high specificity. Validation on a new material is essential before considering clinical use.
Maria Fogelberg   +6 more
wiley   +1 more source

Direct Policy Search for a Risk‐Based Levee Design Framework With Scenario Reduction

open access: yesJournal of Flood Risk Management, Volume 19, Issue 3, September 2026.
ABSTRACT Risk‐based management of coastal flood risk using realistic, process‐based models poses computational challenges, particularly when addressing uncertainties like sea‐level rise. This study explores the use of direct policy search (DPS) as a state‐dependent, adaptive decision‐making approach for upgrading levee systems.
Jingya Wang, David R. Johnson
wiley   +1 more source

Altered Pharmacokinetics and Delayed Sputum Conversion in Tuberculosis Patients Co‐Infected With HIV

open access: yesTropical Medicine &International Health, Volume 31, Issue 9, Page 1261-1272, September 2026.
ABSTRACT Background HIV co‐infection affects host responses and pharmacokinetics (PK) of tuberculosis (TB) treatment. This study assessed the PK of first‐line anti‐TB drugs and clinical outcomes in patients with and without HIV co‐infection. Methods In this prospective observational study, 61 adults with sputum‐positive pulmonary TB, either confirmed ...
Aung Pyae Phyo   +14 more
wiley   +1 more source

The Solar Wind Electron (SWE) Instrument for the Interstellar Mapping and Acceleration Probe Mission. [PDF]

open access: yesSpace Sci Rev
Skoug RM   +33 more
europepmc   +1 more source

Global Flash Drought Prediction Through Evaporative Stress Forecasting

open access: yesGeophysical Research Letters, Volume 53, Issue 16, 28 August 2026.
Abstract Flash droughts pose severe risks to societies and ecosystems due to their sudden onset and rapid intensification. Predicting their vegetation impacts at subseasonal timescales remains difficult. Advances in hybrid physics‐AI models and weather forecasting create new opportunities to enhance the predictability of evaporative stress, a key ...
Qiqi Gou   +8 more
wiley   +1 more source

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