Results 41 to 50 of about 6,100,297 (275)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
L'Atelier du CRH, 2018 The Swedish novelist Jan Fridegård belongs to the so-called proletarian school. The principal aim of proletarian writers was to denounce the social injustices they had suffered and witnessed during their youth and to offer the people a new kind of ...
Caroline Olsson
doaj +1 more source
, 2020 Traditionally, challenges of natural resource management have been addressed with a sectoral policy approach. However, it is increasingly recognised that different sectors are interconnected in a complex and mutually interacting system.
L. V. Heuvel +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Svensk 1800-talslitteratur i världen
Tidskrift för Litteraturvetenskap, 2018 Swedish Literature as World Literature in the Nineteenth Century. Top Selling Novels by Women Writers So far, Swedish literary history has been the construction of a nation’s cultural heritage based on certain authorships. This most certainly was the
Yvonne Leffler
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
RIDE, 2017 Litteraturbanken (The Swedish Literature Bank) is a freely available digital collection of Swedish literary works, ranging from medieval to contemporary literature.
Mats Dahlström, Wout Dillen
doaj +1 more source
The emergence of food waste as an issue in Swedish retail
, 2020 Food waste is acknowledged as a major environmental issue, but the retail sector has only begun to recognise this in recent years. The purpose of this paper is to answer when, how and why food waste became important for retail in Sweden.,A mixed-methods ...
Joacim Rosenlund +3 more
semanticscholar +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source