Results 61 to 70 of about 117,466 (299)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

The Historical and Literary Context of Ateşten Gömlek’s Swedish Translation (Eldskjortan): The Translation Strategy, the Letters Between the Translator and Halide Edib, and the Reception of the Novel in Sweden

İstanbul Üniversitesi Edebiyat Fakültesi Türk Dili ve Edebiyatı Dergisi
This article examines Halide Edib’s reception in Sweden through Eldskjortan (1928), the Swedish translation of her novel Ateşten Gömlek (1922) utilizing Swedish archives based on this translation. For this purpose, the article briefly addresses the first
Ahmed Nuri
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Defining Working-Class Literature(s): A Comparative Approach Between U.S. Working-Class Studies and Swedish Literary History

New Proposals, 2016
The aim of this article is to contribute to the theoretical understanding of the phenomenon of working-class literature through a comparison of how it has developed in two countries—Sweden and the United States—and, more importantly, how it has been ...
Magnus Nilsson, John Lennon
doaj  

”Min tröst var att författa en egen artikel om svamparna”

Tidskrift för Litteraturvetenskap
“My Consolation was to Write my Own Article on Fungi”: Fictional Representations of the Relationship Between Fungi and Humans This article explores fictional representations of fungi, understanding them as a materialization of theoretical ideas about
Sofia Wijkmark
doaj   +1 more source

L’importation de la littérature française : un triple détournement de capital. Réflexions à partir d’une étude de réception journalistique en Suède

Moderna Språk, 2016
The background material of the study consists of articles about French literature gathered between 2010 and 2014 in the Swedish press. The aim of the article is to isolate the most widely discussed French literature from France in the Swedish press ...
Mickaëlle Cedergren, Ylva Lindberg
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Litteraturbanken: the Swedish  Literature Bank [PDF]

, 2017
Litteraturbanken (The Swedish Literature Bank) is a freely available digital collection of Swedish literary works, ranging from medieval to contemporary literature. It is the result of a cooperation between literary and linguistic scholars, research libraries, and editorial societies and academies. The collection consists not only of digital facsimiles,
Dahlström, Mats, Dillen, Wout
openaire   +2 more sources