Results 51 to 60 of about 117,466 (299)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Svensk 1800-talslitteratur i världen
Tidskrift för Litteraturvetenskap, 2018 Swedish Literature as World Literature in the Nineteenth Century. Top Selling Novels by Women Writers So far, Swedish literary history has been the construction of a nation’s cultural heritage based on certain authorships. This most certainly was the
Yvonne Leffler
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Swedenborg: architetture di un visionario
Annali di Ca’ Foscari: Serie OccidentaleThis essay offers an architectural delineation of the universe according to the mystic Emanuel Swedenborg, following his descriptions of houses, towns, and environment in his visions of other worlds.
Perrelli, Franco
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RIDE, 2017 Litteraturbanken (The Swedish Literature Bank) is a freely available digital collection of Swedish literary works, ranging from medieval to contemporary literature.
Mats Dahlström, Wout Dillen
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The Conversational Framework, Democratic Education, and Pedagogic Design in the American Literature Survey : A Case Study [PDF]
, 2016 This presentation attempts to probe the applicability of Diana Laurillard’s “conversational” model of collaborative learning to the teaching of the American Literature Survey at the University of Gävle. For the purpose of exemplification, I have selected
Cananau, Iulian,
core
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Manlighet, mod och moral: Amanda Kerfstedts ”Carl Bergs skoltid”
Barnboken: Tidskrift för Barnlitteraturforskning, 2012 Amanda Kerfstedt’s ”Carl Bergs skoltid” describes a boy’s journey to manhood in late 19th century Sweden. This article pertains that the text contrasts an ideal of masculinity based on physical strength with an ideal emphasizing morality. Although a true
Maria Andersson
doaj +1 more source