Results 181 to 190 of about 30,090 (259)

Artificial Sweeteners and Autoimmune Diseases: Insights From Integrative Bioinformatics and Mendelian Randomization

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
This study provides a novel molecular perspective on the role of AS in ADs development. We identified a positive association between artificially sweetened cereal intake and ADs risk and revealed multiple pathogenic mechanisms involving apoptosis, inflammatory signaling, immune activation, and gut microbiota dysbiosis.
Yupei Liu   +6 more
wiley   +1 more source

Combination of Dietary Fibers From Different Food Origins as a Treatment for Adults With Functional Constipation: A Randomized Clinical Trial

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
This randomized, double‐blind, placebo‐controlled trial evaluated the efficacy of MNS‐36, a combination of soluble and insoluble dietary fibers, in adults with functional constipation. After 28 days, MNS‐36 significantly improved bowel movement frequency, stool consistency, and gastrointestinal symptoms, including bloating and abdominal distension ...
Alessandro Di Minno   +14 more
wiley   +1 more source

Mutational dynamics in patients with del(5q) MDS treated with lenalidomide prior to transfusion dependency—Molecular results from the Sintrarev clinical trial

open access: yesHemaSphere, Volume 10, Issue 6, June 2026.
Abstract Lenalidomide (Len) is the standard of care for red blood cell transfusion‐dependent (TD) patients with myelodysplastic syndromes (MDS) and del(5q). A Phase III clinical trial (SintraRev) demonstrated better efficacy of early treatment with Len in anemic del(5q) MDS patients prior to TD, but clonal evolution with this approach remained ...
Sofía Toribio Castelló   +20 more
wiley   +1 more source

Positionally distinct interferon-stimulated dermal immune-acting fibroblasts promote neutrophil recruitment in Sweet syndrome. [PDF]

open access: yesJ Allergy Clin Immunol
Cavagnero KJ   +17 more
europepmc   +1 more source

Efficacy and Safety of Messenger RNA Vaccines

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims The rapid development of mRNA vaccines has revolutionized infectious disease prevention and cancer immunotherapy. While their efficacy is well established, concerns about safety and immunopathological risks persist. This study aims to evaluate the immunogenicity, safety profiles, and design considerations of mRNA vaccines ...
Kesaobaka Batisani, David Chisompola
wiley   +1 more source

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