Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Improved Sensitivity of a Taste Sensor Composed of Trimellitic Acids for Sweetness. [PDF]
Watanabe T, Kumura S, Kimura S, Toko K.
europepmc +1 more source
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
The efficacy of sweet solutions on dental injection related pain: a systematic review of randomized controlled trials. [PDF]
Altuhafy M, Ahuja TK, Khan J.
europepmc +1 more source
The Impact of Artificial Sweeteners on Human Health and Cancer Association: A Comprehensive Clinical Review. [PDF]
Ghusn W, Naik R, Yibirin M.
europepmc +1 more source
Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Chen‐xi Li, Zhong‐cheng Gong
wiley +1 more source
Transcriptome Analysis Reveals the Mechanism of Cold-Induced Sweetening in Chestnut during Cold Storage. [PDF]
Zhan C, Jia R, Yang S, Zhang M, Peng L.
europepmc +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Prediction of Solvent Composition for Absorption-Based Acid Gas Removal Unit on Gas Sweetening Process. [PDF]
Faqih M+5 more
europepmc +1 more source