Results 61 to 70 of about 5,736 (264)

Artificial Sweeteners

, 2019
Artificial Sweeteners provide the sweetness of natural sugar without the calories and produce a low glycemic response. These sweeteners are used instead of sucrose (table sugar) to sweeten foods and beverages. Consumers and food manufacturers have long been interested in dietary sweeteners to replace sucrose in foods.
openaire   +2 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Studies on Synthetic Sweetening Agents. VIII. Cyclohexylamine, a Metabolite of Sodium Cyclamate

, 1966
Shoji Kojima, Hisashi Ichibagase
openalex   +2 more sources

Influence of temperature and fat content on ideal sucrose concentration, sweetening power, and sweetness equivalence of different sweeteners in chocolate milk beverage [PDF]

, 2014
J.A. Paixão, Juliana Bürger Rodrigues, Erick A. Esmerino, Adriano G. Cruz, Helena María André Bolini   +4 more
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Studies on Synthetic Sweetening Agents. XII. The Binding of Sodium Cyclamate with Bovine Serum Albumin

, 1968
Shoji Kojima, Hisashi Ichibagase
openalex   +2 more sources

Sugar reduction of skim chocolate milk and viability of alternative sweetening through lactose hydrolysis [PDF]

, 2014
X.E. Li, Kannapon Lopetcharat, Yuanjing Qiu, M.A. Drake   +3 more
openalex   +1 more source

Artificial Sweeteners [PDF]

Science, 1965
openaire   +2 more sources

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Studies on Synthetic Sweetening Agents. VII. Absorption and Excretion of Sodium cyclamate. (2)

, 1966
Shoji Kojima, Hisashi Ichibagase, Sadao Iguchi   +2 more
openalex   +2 more sources