Results 41 to 50 of about 812,721 (324)

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

Impact of in vitro digested zinc oxide nanoparticles on intestinal model systems

Particle and Fibre Toxicology, 2022
Background Zinc oxide nanoparticles (ZnO NP) offer beneficial properties for many applications, especially in the food sector. Consequently, as part of the human food chain, they are taken up orally. The toxicological evaluation of orally ingested ZnO NP
Anna Mittag, Alina Singer, Christian Hoera, Martin Westermann, Alexander Kämpfe, Michael Glei   +5 more
doaj   +1 more source

Cellular Uptake and Toxicological Effects of Differently Sized Zinc Oxide Nanoparticles in Intestinal Cells

Toxics, 2021
Due to their beneficial properties, the use of zinc oxide nanoparticles (ZnO NP) is constantly increasing, especially in consumer-related areas, such as food packaging and food additives, which is leading to an increased oral uptake of ZnO NP ...
Anna Mittag, Christian Hoera, Alexander Kämpfe, Martin Westermann, Jochen Kuckelkorn, Thomas Schneider, Michael Glei   +6 more
doaj   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Focus on One Swimming Stroke or Compete in Multiple: How Much Specialization Is Needed to Become a World-Class Female Swimmer?

Journal of Functional Morphology and Kinesiology
Objectives: To investigate performance development and variety in swimming strokes of female swimmers from early junior to elite age. Methods: A total of 194,788 race times of female 200 m swimmers representing 77 nations were ranked at peak performance ...
Dennis-Peter Born, Jenny Lorentzen, Jesús J. Ruiz-Navarro, Thomas Stöggl, Michael Romann, Glenn Björklund   +5 more
doaj   +1 more source

Effects of the Basic Period in Swimming Training with the Age Group [PDF]

Sport Mont, 2019
Development of aerobic capacity and endurance is important part of basic period in swimming training for age groups. The focus of this study was monitoring the progress of a group of 17 male swimmers, aged between 12 to 14 from HAPK Mladost, Zagreb. They
Goran Leko, Klara Siljeg, Tatjana Greguranic   +2 more
doaj   +1 more source

The kinematic profile of ventral swimming start: sex diversity

Frontiers in Physiology, 2023
It has been suggested that sex distinctions in physiology may affect the swimming performance of each sex differently. Yet, sex-based performance dependency has not been taken into consideration by most of the researchers evaluating swimming start ...
Daria Malgorzata Rudnik, Daria Malgorzata Rudnik, Marek Rejman, Joao Paulo Vilas-Boas, Joao Paulo Vilas-Boas   +4 more
doaj   +1 more source

Morphology, Swimming Performance and Propulsive Mode of Six Co-occurring Hydromedusae [PDF]

, 2002
Jet propulsion, based on examples from the Hydrozoa, has served as a valuable model for swimming by medusae. However, cnidarian medusae span several taxonomic classes (collectively known as the Medusazoa) and represent a diverse array of morphologies and
Colin, Sean, Costello, John H.
core   +2 more sources

Dispersion of biased swimming microorganisms in a fluid flowing through a tube

, 2010
Classical Taylor-Aris dispersion theory is extended to describe the transport of suspensions of self-propelled dipolar cells in a tubular flow. General expressions for the mean drift and effective diffusivity are determined exactly in terms of axial ...
Aris R., Bees M. A., Hill N. A., Pedley T. J., Taylor G. I., Taylor G. I., Taylor G. I.   +6 more
core   +1 more source

Competition-Based Success Factors During the Talent Pathway of Elite Male Swimmers

Frontiers in Sports and Active Living, 2020
Marginal differences in race results between top swimmers have evoked the interest in competition-based success factors of long-term athlete development.
Dennis-Peter Born, Dennis-Peter Born, Ishbel Lomax, Stephan Horvath, Elena Meisser, Elena Meisser, Philipp Seidenschwarz, Philipp Seidenschwarz, David Burkhardt, Michael Romann   +9 more
doaj   +1 more source