Results 81 to 90 of about 172,330 (263)

UPF3B modulates endoplasmic reticulum stress through interaction with inositol-requiring enzyme-1α

Cell Death and Disease
The unfolded protein response (UPR) is a conserved and adaptive intracellular pathway that relieves the endoplasmic reticulum (ER) stress by activating ER transmembrane stress sensors.
XingSheng Sun, Ruqin Lin, Xinxia Lu, Zhikai Wu, Xueying Qi, Tianqing Jiang, Jun Jiang, Peiqiang Mu, Qingmei Chen, Jikai Wen, Yiqun Deng   +10 more
doaj   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats

ESC Heart Failure, Volume 12, Issue 2, Page 1304-1315, April 2025.
Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction
Einar Sjaastad Nordén, Bård Andre Bendiksen, Kaja Knudsen Bergo, Emil Knut Stenersen Espe, Gary McGinley, Almira Hasic, Ida Marie Hauge‐Iversen, Hege Katrin Ugland, Xin Shen, Michael Frisk, Nishani S. Mabotuwana, William E. Louch, Rizwan I. Hussain, Lili Zhang, Ivar Sjaastad, Alessandro Cataliotti, Geir Christensen   +16 more
wiley   +1 more source

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source

Cytolethal distending toxin from Glaesserella parasuis induces ferroptosis in porcine alveolar macrophages and mice

Veterinary Research
Glaesserella parasuis cytolethal distending toxin (GpCDT) is a bacterial genotoxin whose main action is to activate DNA damage responses, induce cell cycle arrest, and induce the apoptosis of host cells.
Shiyu Xu, Li Lei, Zhen Yang, Yu Wang, Senyan Du, Qin Zhao, Xiaobo Huang, Sanjie Cao, Rui Wu, Yiping Wang, Qigui Yan, Yiping Wen   +11 more
doaj   +1 more source

Food Safety Management and Mycotoxins Nexus: A Systematic Review of Mycotoxins Toxicity, Detoxification, Nutritional Impacts, and Economic Importance

Food Safety and Health, EarlyView.
The graphical abstract illustrates the interconnected relationship between food safety management, mycotoxin toxicity, and detoxification strategies, highlighting how preventive measures across the food chain can minimize mycotoxin contamination and reduce adverse health effects in humans/animals.
Chinaza Godswill Awuchi
wiley   +1 more source

Care and COVID 19: Lessons for liberals and neoliberals

Child &Family Social Work, EarlyView., 2023
Abstract Within the liberal political traditions, care is regarded as a private matter, a problem of ethics rather than justice. Social justice is framed as an issue of economics (re/distribution), culture (recognition) and/or politics (representation).
Kathleen Lynch
wiley   +1 more source

Trends in seroprevalence of influenza A virus infections in pigs in France (2008–2022)

Porcine Health Management
Background Swine influenza A viruses (swIAV) are highly contagious zoonotic pathogens that cause an acute respiratory infection in pigs, presenting substantial economic and health risks for animals and farmers.
Séverine Hervé, Nicolas Rose, Nicolas Barbier, Stéphane Quéguiner, Stéphane Gorin, Roselyne Fonseca, Gaëtan Pinsard, Gautier Richard, Agnès Jardin, Gaëlle Simon   +9 more
doaj   +1 more source

Reframing Technology and Ethics in Corneal Xenotransplantation: A Scoping Review of Standards and Safety in Ophthalmology

Health Care Science, EarlyView.
Bringing attention to the moral dilemmas raised by xenotransplantation and the continuous creation of standardized frameworks for donor technology and biosafety risk management, with a focus on striking a balance between patient safety, medical innovation, and ethical obligation.
Sankhajyoti Saha, Moubani Dutta, Agnihiya Bosu   +2 more
wiley   +1 more source

Chicken‐linked multidrug‐resistant Campylobacter jejuni infections among Chinese children

iMetaOmics, EarlyView.
Campylobacter is a leading cause of pediatric diarrhea, but its genomic epidemiology and antimicrobial resistance in China remain poorly defined. We conducted genomic surveillance of 3492 children with diarrhea in two pediatric hospitals in Zhejiang Province in 2017, 2018, and 2021, combining culture, whole‐genome sequencing, and source‐attribution ...
Dongyan Shao, Yuchen Wu, Zhaoju Deng, Hanyu Wang, Can Cui, Jianzhong Shen, Julian Parkhill, Yang Wang, Rong Zhang, Dejun Liu   +9 more
wiley   +1 more source