Results 61 to 70 of about 37,459 (182)

sGC stimulator BAY 41‐8543 improves survival and ventricular function in a rat model of doxorubicin‐induced cardiomyopathy with nephrotic syndrome

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/soluble guanylyl cyclase (sGC)/cGMP pathway has been reported in anthracycline‐induced cardiomyopathy.
Olga Gawrys, Petra Škaroupková, Soňa Kikerlová, Zdeňka Vaňourková, Martina Hüttl, Olga Lenčová, Kasin Yadunandam Anandam, Svenja Stomberg, Sönke Behrends, Barbara Szeiffová Bačová, Matúš Sykora, Lisa Dietz, Peter Sandner, Luděk Červenka, Martin Štěrba   +14 more
wiley   +1 more source

Diagnostics and Surveillance for Swine Influenza [PDF]

, 2012
Collective knowledge regarding the occurrence of influenza among swine is incomplete due to inconsistent surveillance of swine populations. In this chapter, we review what surveillance activities exist and some of the practical challenges encountered. Furthermore, to support robust surveillance activities, accurate laboratory assays are needed for the ...
Detmer, Susan, Gramer, Marie, Goyal, Sagar, Torremorell, Montserrat, Torrison, Jerry   +4 more
openaire   +2 more sources

A commentary on Zuniga‐Montanez and Davies et al.: how did COVID‐19 affect young children's language environment and language development? A scoping review

Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 602-605, April 2025.
It was early 2020, a week or two into Hilary Term, what everyone else calls Spring Term, but we at Oxford love our arcane traditions. I recall one of my graduate students, from China, coming to me ashen‐faced at the end one of my lectures on the effects of bilingualism on the linguistic and cognitive development of young learners.
Hamish Chalmers
wiley   +1 more source

Influenza A virus vaccines for swine

Veterinary Microbiology, 2017
Economic losses due to influenza A virus (IAV) infections are substantial and a global problem, ranking among the top three major health challenges in the swine industry. Currently, H1 and H3 subtypes circulate in pigs globally associated with different combinations of N1 and N2 subtypes; however, the origin, gene constellation, and antigenic makeup of
Amy L, Vincent, Daniel R, Perez, Daniela, Rajao, Tavis K, Anderson, Eugenio J, Abente, Rasna R, Walia, Nicola S, Lewis   +6 more
openaire   +3 more sources

Human-Origin Influenza A(H3N2) Viruses Revealed in Swine Farms During the Period 2022–2025 in Kazakhstan

Animals
Seasonal human influenza A viruses (H1N1 and H3N2) are frequently transmitted to swine populations. Continued transmission of these viruses among swine results in genetic and phenotypic changes, creating new lineages of swine influenza viruses that ...
Nailya Klivleyeva, Tatyana Glebova, Nurbol Saktaganov, Assem Baimukhametova, Mereke Kalkozhayeva, Nuray Ongarbayeva, Indira Ibragimova, Primkul Ibragimov, Richard Webby   +8 more
doaj   +1 more source

Knocking Out Two Polyphenol Oxidase Genes Significantly Improves Recombinant Protein Purification in Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
ABSTRACT Efficient purification remains a key technical challenge affecting the recovery efficiency of recombinant proteins in plant‐based systems. Complex metabolites, particularly polyphenols, often cause recombinant protein aggregation during purification.
Hai‐Ping Diao, Hui‐Xin Meng, Xue‐Jiao Xu, Zeng‐Lin Zhang, Jian‐Feng Zhang, Yong‐Feng Guo, Inhwan Hwang, Shi‐Jian Song   +7 more
wiley   +1 more source

Swine Flu 2009, Morbidity and Mortality in a Sample of patients Admitted in Al-kindy Teaching Hospital

مجله كليه طب الكندي, 2012
Objective; swine flu is known to be caused by influenza A subtypes H1N1,H1N2, H2N3, H3N1, and H3N2, was first proposed to be a disease related to human flu during the 1918 flu pandemic, Iraq face the epidemic of 2009, many patients admitted to the ...
Hamzah Qoneed Oleiwi, Rushdi A.H. Kubba, Mohammed Abdul Jabbar Salman, Faris Abdul Kareem Khazaal   +3 more
doaj   +2 more sources

An age‐associated decline in the role of the sarcoplasmic reticulum and associated calcium‐handling proteins sets the pace for sinoatrial node function

The Journal of Physiology, EarlyView.
Abstract figure legend Stable, responsive pacemaking in the sinoatrial node is driven by the activity of the funny current (membrane clock), interplay of calcium cycling and release from the sarcoendoplasmic reticulum with depolarising sodium‐calcium exchange current (calcium clock). With increasing age, key proteins associated with calcium cycling are
Sandra A. Jones, Fiona S. Godbeer, Matthew K. Lancaster   +2 more
wiley   +1 more source

A single dose vaccination with an elastase-dependent H1N1 live attenuated swine influenza virus protects pigs from challenge with 2009 pandemic H1N1 virus

Acta Veterinaria, 2014
The 2009 outbreak of H1N1 influenza A viruses in humans underscored the importance of pigs in influenza A virus evolution and the emergence of novel viruses with pandemic potential.
Mašić Aleksandar, Woldeab Niziti, Embury-Hyatt Carissa, Zhou Yan, Babiuk Shawn   +4 more
doaj   +1 more source

Neural modulation of ocular immunity: Exploring a sympathetic‐macrophage neuroimmune link in the human ciliary body

Journal of Anatomy, Volume 249, Issue 3, Page 565-577, September 2026.
Using microscopy and 3D confocal imaging on seven cadaveric eyes, we identified sympathetic nerves closely associated with β₂‐adrenergic receptor‐expressing macrophages in the human ciliary body (CB). These findings suggest a sympathetic‐macrophage neuroimmune link in the CB, potentially influencing ocular inflammation and degeneration, warranting ...
Tanya S. Karakyriakou, Claire Mackaaij, Mark van Zijverden, Hendrik A. Messal, Jeannette Ossewaarde‐van Norel, Ronald L. A. W. Bleys, Cindy G. J. Cleypool   +6 more
wiley   +1 more source