Results 1 to 10 of about 560,921 (309)

Identification and Subtyping of Salmonella Isolates Using Matrix-Assisted Laser Desorption–Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF)

Microorganisms, 2022
Subtyping of bacterial isolates of the same genus and species is an important tool in epidemiological investigations. A number of phenotypic and genotypic subtyping methods are available; however, most of these methods are labor-intensive and time ...
Anil K. Persad, Hanan A. Fahmy, Nicholas Anderson, Jing Cui, Zeynal Topalcengiz, Saharuetai Jeamsripong, Patrick M. Spanninger, Robert L. Buchanan, Kalmia E. Kniel, Michele T. Jay-Russell, Michelle D. Danyluk, Gireesh Rajashekara, Jeffrey T. LeJeune   +12 more
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Meta-Ribosomalomics: RNA Sequencing Is an Unbiased Method for Parasite Detection of Different Sample Types

Frontiers in Microbiology, 2021
In this perspective article, we review the past use of ribosomal sequences to address scientific and diagnostic questions. We highlight a variety of sequencing approaches including metagenomics and DNA barcoding and their different demands and ...
Claudia Wylezich, Dirk Höper
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Subtyping based on immune cell fractions reveal heterogeneity of cardiac fibrosis in end-stage heart failure

Frontiers in Immunology, 2023
BackgroundA central issue hindering the development of effective anti-fibrosis drugs for heart failure is the unclear interrelationship between fibrosis and the immune cells. This study aims at providing precise subtyping of heart failure based on immune
Shangjie Zou, Shangjie Zou, Bee Luan Khoo, Bee Luan Khoo, Bee Luan Khoo   +4 more
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Ordinal SuStaIn: Subtype and Stage Inference for Clinical Scores, Visual Ratings, and Other Ordinal Data

Frontiers in Artificial Intelligence, 2021
Subtype and Stage Inference (SuStaIn) is an unsupervised learning algorithm that uniquely enables the identification of subgroups of individuals with distinct pseudo-temporal disease progression patterns from cross-sectional datasets.
Alexandra L. Young, Alexandra L. Young, Alexandra L. Young, Jacob W. Vogel, Jacob W. Vogel, Leon M. Aksman, Peter A. Wijeratne, Peter A. Wijeratne, Arman Eshaghi, Arman Eshaghi, Neil P. Oxtoby, Neil P. Oxtoby, Steven C. R. Williams, Daniel C. Alexander, Daniel C. Alexander, for the Alzheimer’s Disease Neuroimaging Initiative   +15 more
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Identification of mitochondrial-related genes as potential biomarkers for the subtyping and prediction of Alzheimer’s disease

Frontiers in Molecular Neuroscience, 2023
IntroductionAlzheimer’s disease (AD) is a progressive and debilitating neurodegenerative disorder prevalent among older adults. Although AD symptoms can be managed through certain treatments, advancing the understanding of underlying disease mechanisms ...
Wenhao Ma, Wenhao Ma, Wenhao Ma, Yuelin Su, Peng Zhang, Guoqing Wan, Guoqing Wan, Xiaoqin Cheng, Changlian Lu, Changlian Lu, Xuefeng Gu, Xuefeng Gu   +11 more
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Comprehensive analysis of mitophagy-related genes in NSCLC diagnosis and immune scenery: based on bulk and single-cell RNA sequencing data

Frontiers in Immunology, 2023
Lung cancer is the main cause of cancer-related deaths, and non-small cell lung cancer (NSCLC) is the most common type. Understanding the potential mechanisms, prognosis, and treatment aspects of NSCLC is essential. This study systematically analyzed the
Haibo Yu, Haibo Yu, Haibo Yu, Qingtao Liu, Mingming Jin, Mingming Jin, Gang Huang, Gang Huang, Gang Huang, Qianqian Cai, Qianqian Cai   +10 more
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Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer

The Journal of Pathology: Clinical Research, 2020
Histological ‘phenotypic subtypes’ that classify patients into four groups (immune, canonical, latent and stromal) have previously been demonstrated to stratify survival in a stage I–III colorectal cancer (CRC) pilot cohort. However, clinical utility has
Antonia K Roseweir, James H Park, Sanne ten Hoorn, Arfon GMT Powell, Susan Aherne, Campbell SD Roxburgh, Donald C McMillan, Paul G Horgan, Elizabeth Ryan, Kieran Sheahan, Louis Vermeulen, James Paul, Andrea Harkin, Janet Graham, Owen Sansom, David N Church, Ian Tomlinson, Mark Saunders, Tim J Iveson, Joanne Edwards   +19 more
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Detailed Evaluation of Data Analysis Tools for Subtyping of Bacterial Isolates Based on Whole Genome Sequencing: Neisseria meningitidis as a Proof of Concept

Frontiers in Microbiology, 2019
Whole genome sequencing is increasingly recognized as the most informative approach for characterization of bacterial isolates. Success of the routine use of this technology in public health laboratories depends on the availability of well-characterized ...
Assia Saltykova, Assia Saltykova, Wesley Mattheus, Sophie Bertrand, Nancy H. C. Roosens, Kathleen Marchal, Kathleen Marchal, Sigrid C. J. De Keersmaecker   +7 more
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Recent Molecular Evolution of Human Metapneumovirus (HMPV): Subdivision of HMPV A2b Strains

Microorganisms, 2020
Human metapneumovirus (HMPV) is a major etiological agent of acute respiratory infections in humans. HMPV has been circulating worldwide for more than six decades and is currently divided into five agreed-upon subtypes: A1, A2a, A2b, B1, and B2. Recently,
Naganori Nao, Miwako Saikusa, Ko Sato, Tsuyoshi Sekizuka, Shuzo Usuku, Nobuko Tanaka, Hidekazu Nishimura, Makoto Takeda   +7 more
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Subtyping of Swine Influenza Viruses Using a High-Throughput Real-Time PCR Platform

Frontiers in Cellular and Infection Microbiology, 2018
Influenza A viruses (IAVs) are important human and animal pathogens with high impact on human and animal health. In Denmark, a passive surveillance program for IAV in pigs has been performed since 2011, where screening tests and subsequent subtyping are ...
Nicole B. Goecke, Jesper S. Krog, Charlotte K. Hjulsager, Kerstin Skovgaard, Timm C. Harder, Solvej Ø. Breum, Lars E. Larsen   +6 more
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