Results 1 to 10 of about 43,101 (266)

Sentinel Surveillance of Influenza A in Libya: Subtyping and Genomic Analysis During Recent Seasons (2022–2024) [PDF]

open access: yesTropical Medicine and Infectious Disease
Influenza sentinel surveillance in Libya was formally established in 2022 by the Libyan National Center for Disease Control (NCDC). Between 2022 and 2024, a total of 1864 nasopharyngeal specimens were collected from patients presenting with influenza ...
Mahmud Azbida   +12 more
doaj   +2 more sources

Identification and Subtyping of Salmonella Isolates Using Matrix-Assisted Laser Desorption–Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF)

open access: yesMicroorganisms, 2022
Subtyping of bacterial isolates of the same genus and species is an important tool in epidemiological investigations. A number of phenotypic and genotypic subtyping methods are available; however, most of these methods are labor-intensive and time ...
Anil K. Persad   +12 more
doaj   +1 more source

Meta-Ribosomalomics: RNA Sequencing Is an Unbiased Method for Parasite Detection of Different Sample Types

open access: yesFrontiers in Microbiology, 2021
In this perspective article, we review the past use of ribosomal sequences to address scientific and diagnostic questions. We highlight a variety of sequencing approaches including metagenomics and DNA barcoding and their different demands and ...
Claudia Wylezich, Dirk Höper
doaj   +1 more source

Subtyping based on immune cell fractions reveal heterogeneity of cardiac fibrosis in end-stage heart failure

open access: yesFrontiers in Immunology, 2023
BackgroundA central issue hindering the development of effective anti-fibrosis drugs for heart failure is the unclear interrelationship between fibrosis and the immune cells. This study aims at providing precise subtyping of heart failure based on immune
Shangjie Zou   +4 more
doaj   +1 more source

Ordinal SuStaIn: Subtype and Stage Inference for Clinical Scores, Visual Ratings, and Other Ordinal Data

open access: yesFrontiers in Artificial Intelligence, 2021
Subtype and Stage Inference (SuStaIn) is an unsupervised learning algorithm that uniquely enables the identification of subgroups of individuals with distinct pseudo-temporal disease progression patterns from cross-sectional datasets.
Alexandra L. Young   +15 more
doaj   +1 more source

Identification of mitochondrial-related genes as potential biomarkers for the subtyping and prediction of Alzheimer’s disease

open access: yesFrontiers in Molecular Neuroscience, 2023
IntroductionAlzheimer’s disease (AD) is a progressive and debilitating neurodegenerative disorder prevalent among older adults. Although AD symptoms can be managed through certain treatments, advancing the understanding of underlying disease mechanisms ...
Wenhao Ma   +11 more
doaj   +1 more source

Comprehensive analysis of mitophagy-related genes in NSCLC diagnosis and immune scenery: based on bulk and single-cell RNA sequencing data

open access: yesFrontiers in Immunology, 2023
Lung cancer is the main cause of cancer-related deaths, and non-small cell lung cancer (NSCLC) is the most common type. Understanding the potential mechanisms, prognosis, and treatment aspects of NSCLC is essential. This study systematically analyzed the
Haibo Yu   +10 more
doaj   +1 more source

Constructor Subtyping [PDF]

open access: yes, 1999
Constructor subtyping is a form of subtyping in which an inductive type A is viewed as a subtype of another inductive type B if B has more constructors than A. Its (potential) uses include proof assistants and functional programming languages. In this paper, we introduce and study the properties of a simply typed lambda-calculus with record types and ...
Gilles Barthe, Maria João Frade
openaire   +2 more sources

Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer

open access: yesThe Journal of Pathology: Clinical Research, 2020
Histological ‘phenotypic subtypes’ that classify patients into four groups (immune, canonical, latent and stromal) have previously been demonstrated to stratify survival in a stage I–III colorectal cancer (CRC) pilot cohort. However, clinical utility has
Antonia K Roseweir   +19 more
doaj   +1 more source

Explicit effect subtyping [PDF]

open access: yesJournal of Functional Programming, 2020
Abstract As popularity of algebraic effects and handlers increases, so does a demand for their efficient execution. Eff, an ML-like language with native support for handlers, has a subtyping-based effect system on which an effect-aware optimising compiler could be built. Unfortunately, in our experience, implementing optimisations for
Karachalias, Georgios   +4 more
openaire   +5 more sources

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