Results 21 to 30 of about 560,921 (309)

Evaluation and comparison of multi-omics data integration methods for cancer subtyping

PLoS Comput. Biol., 2021
Computational integrative analysis has become a significant approach in the data-driven exploration of biological problems. Many integration methods for cancer subtyping have been proposed, but evaluating these methods has become a complicated problem ...
Ran Duan, Lin Gao, Yong Gao, Yuxuan Hu, Han Xu, Mingfeng Huang, Kuo Song, Hongda Wang, Yongqiang Dong, Chaoqun Jiang, Chenxing Zhang, Song-Wei Jia   +11 more
semanticscholar   +1 more source

Molecular subtyping and genomic profiling expand precision medicine in refractory metastatic triple-negative breast cancer: the FUTURE trial

Cell Research, 2020
Triple-negative breast cancer (TNBC) is a highly heterogeneous disease, and molecular subtyping may result in improved diagnostic precision and targeted therapies.
Yi-Zhou Jiang, Yin Liu, Yi Xiao, Xin Hu, Lin Jiang, Wen-Jia Zuo, Ding Ma, Jiahan Ding, Xiao-Yu Zhu, J. Zou, C. Verschraegen, D. Stover, V. Kaklamani, Zhong-Hua Wang, Z. Shao   +14 more
semanticscholar   +1 more source

Molecular characterization of Blastocystis sp. in Chinese bamboo rats (Rhizomys sinensis)

Parasite, 2021
Blastocystis sp., a parasitic eukaryote, widely colonizes the intestines of humans and a large number of animals, including rodents and lagomorphs. More than 30 million bamboo rats (Rhizomys sinensis) are farmed in China as a source of meat for human ...
Song Junke, Yang Xin, Ma Xun, Wu Xuemei, Wang Yuxin, Li Zhili, Liu Guohua, Zhao Guanghui   +7 more
doaj   +1 more source

Evaluation of Next-Generation Sequencing Applied to Cryptosporidium parvum and Cryptosporidium hominis Epidemiological Study

Pathogens, 2022
Background. Nowadays, most of the C. parvum and C. hominis epidemiological studies are based on gp60 gene subtyping using the Sanger sequencing (SgS) method. Unfortunately, SgS presents the limitation of being unable to detect mixed infections.
Eloïse Bailly, Stéphane Valot, Anne Vincent, Yannis Duffourd, Nadège Grangier, Martin Chevarin, Damien Costa, Romy Razakandrainibe, Loïc Favennec, Louise Basmaciyan, Frédéric Dalle   +10 more
doaj   +1 more source

MOVICS: an R package for multi-omics integration and visualization in cancer subtyping

bioRxiv, 2020
Summary Stratification of cancer patients into distinct molecular subgroups based on multi-omics data is an important issue in the context of precision medicine. Here we present MOVICS, an R package for multi-omics integration and visualization in cancer
Xiao-Fan Lu, Jia-Lin Meng, Yujie Zhou, Liyun Jiang, Fang-Rong Yan   +4 more
semanticscholar   +1 more source

Genus, Species, and Subspecies Classification of Salmonella Isolates by Proteomics

Applied Sciences, 2021
Identification of bacteria by mass spectrometry offers the potential of a high-throughput non-targeted method to determine the presence of Salmonella. While MALDI-TOF mass spectrometry can identify Salmonella at the genus and species level, few studies ...
Shu-Hua Chen, Christine H. Parker, Timothy R. Croley, Melinda A. McFarland   +3 more
doaj   +1 more source

Breast Cancer Cell Line Classification and Its Relevance with Breast Tumor Subtyping

Journal of Cancer, 2017
Breast cancer cell lines have been widely used for breast cancer modelling which encompasses a panel of diseases with distinct phenotypical associations.
Xiaofeng Dai, Hong-Ye Cheng, Zhonghu Bai, Jia Li   +3 more
semanticscholar   +1 more source

Subtyping of Human Papillomavirus-Positive Cervical Cancers Based on the Expression Profiles of 50 Genes

Frontiers in Immunology, 2022
BackgroundHuman papillomavirus-positive (HPV+) cervical cancers are highly heterogeneous in molecular and clinical features. However, the molecular classification of HPV+ cervical cancers remains insufficiently unexplored.MethodsBased on the expression ...
Xiaojun Zhu, Shengwei Li, Shengwei Li, Shengwei Li, Jiangti Luo, Jiangti Luo, Jiangti Luo, Xia Ying, Zhi Li, Yuanhe Wang, Mengmeng Zhang, Tianfang Zhang, Peiyue Jiang, Xiaosheng Wang, Xiaosheng Wang, Xiaosheng Wang   +15 more
doaj   +1 more source

A coalgebraic semantics of subtyping [PDF]

, 2001
Subtyping is a central notion in object-oriented programming. In this paper we investigate how the coalgebraic semantics of objects accounts for subtyping.
Erik Poll, Poll, Erik
core   +1 more source

Activity of Wnt/PCP Regulation Pathway Classifies Patients of Low-Grade Glioma Into Molecularly Distinct Subgroups With Prognostic Difference

Frontiers in Oncology, 2021
Wingless/Int-1 (Wnt) signaling is one of the most well-known oncogenic pathways. Numerous studies have uncovered an aberrant expression of Wnt in cancer and its association with multiple oncogenic processes, such as cell proliferation, epithelial ...
Meng Zhang, Meng Zhang, Meng Zhang, Dan Wang, Lan Su, Jingjiao Ma, Sizhen Wang, Meng Cui, Shunming Hong, Bing Guan, Xiaodong Ma   +10 more
doaj   +1 more source