Results 11 to 20 of about 560,921 (309)

BRACS: A Dataset for BReAst Carcinoma Subtyping in H&E Histology Images [PDF]

Database J. Biol. Databases Curation, 2021
Breast cancer is the most commonly diagnosed cancer and registers the highest number of deaths for women. Advances in diagnostic activities combined with large-scale screening policies have significantly lowered the mortality rates for breast cancer ...
N. Brancati, A. Anniciello, Pushpak Pati, D. Riccio, G. Scognamiglio, G. Jaume, G. De Pietro, M. Bonito, A. Foncubierta, G. Botti, M. Gabrani, F. Feroce, Maria Frucci   +12 more
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Accuracy of Gallium-68 Pentixafor Positron Emission Tomography–Computed Tomography for Subtyping Diagnosis of Primary Aldosteronism

JAMA Network Open, 2023
This diagnostic study investigates the accuracy of gallium-68 pentixafor positron emission tomography–computed tomography vs adrenal vein sampling in subtyping diagnosis of primary aldosteronism.
Jin-Bo Hu, Ting-Ting Xu, Hang Shen, Ying Song, Jun Yang, Aipin Zhang, Haoyuan Ding, Nai-Guo Xing, Zhuoyuan Li, Lin Qiu, Lin-Qiang Ma, Yi Yang, Zheng-Ping Feng, Zhi-Peng Du, Wen-Wen He, Yue Sun, Jun Cai, Qi-Fu Li, Yue Chen, Shu-Min Yang   +19 more
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Heterogeneity of triple negative breast cancer: Current advances in subtyping and treatment implications

Journal of experimental & clinical cancer research : CR, 2022
As the field of translational ‘omics has progressed, refined classifiers at both genomic and proteomic levels have emerged to decipher the heterogeneity of breast cancer in a clinically-applicable way.
Karama Asleh, Nazia Riaz, T. Nielsen
semanticscholar   +1 more source

Triple-negative breast cancer molecular subtyping and treatment progress

Breast Cancer Research, 2020
Triple-negative breast cancer (TNBC), a specific subtype of breast cancer that does not express estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth factor receptor 2 (HER-2), has clinical features that include high invasiveness,
Li Yin, Jiang-jie Duan, X. Bian, Shi-Cang Yu   +3 more
semanticscholar   +1 more source

A framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA

Nature Communications, 2022
Cell-free DNA (cfDNA) has the potential to inform tumor subtype classification and help guide clinical precision oncology. Here we develop Griffin, a framework for profiling nucleosome protection and accessibility from cfDNA to study the phenotype of ...
Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A. Cruikshank, K. Santos, Caroline Kikawa, J. Hiatt, Robert D. Patton, N. De Sarkar, K. Collier, A. Hoge, Katharine Chen, Anat Zimmer, Zachary T. Weber, M. Adil, Jonathan B. Reichel, P. Polak, V. Adalsteinsson, Peter S. Nelson, D. MacPherson, H. Parsons, D. Stover, G. Ha   +22 more
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Municipal and neighbourhood level wastewater surveillance and subtyping of an influenza virus outbreak

Scientific Reports, 2022
Recurrent influenza epidemics and pandemic potential are significant risks to global health. Public health authorities use clinical surveillance to locate and monitor influenza and influenza-like cases and outbreaks to mitigate hospitalizations and ...
É. Mercier, P. D'Aoust, Ocean Thakali, N. Hegazy, Jian-jun Jia, Zhihao Zhang, Walaa A. M. Eid, J. Plaza-Diaz, M. P. Kabir, Wan-Ting Fang, Aaron Cowan, Sean Stephenson, L. Pisharody, A. MacKenzie, T. Graber, S. Wan, R. Delatolla   +16 more
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Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets

Science Advances, 2021
Three major molecular subtypes of Alzheimer’s disease are identified, cross-validated, and characterized across 1543 individuals. Alzheimer’s disease (AD), the most common form of dementia, is recognized as a heterogeneous disease with diverse ...
Ryan A. Neff, Ming-Hui Wang, Sezen Vatansever, Lei Guo, Ming Chen, Qian Wang, E. Wang, Emrin Horgusluoglu-Moloch, Won-min Song, Ai-Qun Li, Emilie L. Castranio, Julia Tcw, L. Ho, A. Goate, V. Fossati, S. Noggle, S. Gandy, M. Ehrlich, P. Katsel, E. Schadt, Dongming Cai, K. Brennand, V. Haroutunian, Bin Zhang   +23 more
semanticscholar   +1 more source

Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets.

Cell Metabolism, 2020
Triple-negative breast cancer (TNBC) remains an unmet medical challenge. We investigated metabolic dysregulation in TNBCs by using our multi-omics database (n = 465, the largest to date).
Yue Gong, P. Ji, Yun-Song Yang, S. Xie, Tian-Jian Yu, Yi Xiao, M. Jin, Ding Ma, Lin-Wei Guo, Yuchen Pei, W. Chai, Da-Qiang Li, F. Bai, F. Bertucci, Xin Hu, Yi-Zhou Jiang, Z. Shao   +16 more
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cfDNA methylome profiling for detection and subtyping of small cell lung cancers

Nature Cancer, 2022
Small cell lung cancer (SCLC) is characterized by morphologic, epigenetic and transcriptomic heterogeneity. Subtypes based upon predominant transcription factor expression have been defined that, in mouse models and cell lines, exhibit potential ...
Francesca Chemi, S. Pearce, A. Clipson, S. Hill, A. Conway, Sophie A. Richardson, Katarzyna Kamieniecka, Rebecca Caeser, Daniel J White, S. Mohan, Victoria Foy, K. Simpson, M. Galvin, K. Frese, L. Priest, J. Egger, Alastair R. W. Kerr, P. Massion, J. Poirier, Gerard Brady, F. Blackhall, D. Rothwell, C. Rudin, C. Dive   +23 more
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The Duality of Subtyping [PDF]

, 2020
Subtyping is a concept frequently encountered in many programming languages and calculi. Various forms of subtyping exist for different type system features, including intersection types, union types or bounded quantification. Normally these features are
Oliveira, Bruno C. d. S., Shaobo, Cui, Dos Santos Oliveira, BC, Cui, S, Rehman, B, Rehman, Baber   +5 more
core   +1 more source