Results 71 to 80 of about 1,326,939 (222)

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase [PDF]

, 2010
This work was supported by the Medical Research Council and the Scottish Funding Council.Influenza virus sialidase has an essential role in the virus’ life cycle.
Russell, Rupert James Martin, Thomson, Robin J, Dyason, Jeffrey C, von Itzstein, M, Naffakh, Nadia, Nadia Naffakh, Mark von Itzstein, Faith J. Rose, Rameix-Welti, Marie-Anne, Robin J. Thomson, Dyason, JC, Rupert J. M. Russell, van der Werf, S, Russell, Rupert J M, Santosh Rudrawar, Rose, Faith J, Russell, Rupert JM, Kerry, Philip Stephen, Jeffrey C. Dyason, von Itzstein, Mark, Thomson, RJ, Rudrawar, S, Marie-Anne Rameix-Welti, Kerry, Philip S, Rose, FJ, Naffakh, N, Rameix-Welti, MA, Philip S. Kerry, van Der Werf, Sylvie, Rudrawar, Santosh, Sylvie van der Werf   +30 more
core   +1 more source

Influenza A Virus Diversity and Transmission in Exhibition Swine [PDF]

Journal of Infectious Diseases, 2015
(See the major article by Nelson et al on pages 173–82.) Swine are permissive to infections with both avian and human influenza A viruses, facilitating genomic reassortment among viruses from multiple host species. As a result, swine have been identified as mixing vessels for influenza A viruses and a source of emergence for novel viruses, including
Baranovich, Tatiana, Bahl, Justin
openaire   +2 more sources

Toward Predicting Pandemic Potential: A Comparative Analysis of Virus‐Host Interactions Between Diverse Influenza A Viruses and the Human Innate Immune System

PROTEOMICS, EarlyView.
ABSTRACT Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range of IAVs is shaped by species‐specific virus‐host interactions, and several host barriers have been identified that restrict the adaptation ...
Antoine Gerodez, Melanie Dos Santos, Mikaël Attia, Killian De Geest, Ibrahim Hamid, Rodrigue Tesse, Ilham Fdillate, Marc Boschmans, Steven Van Borm, Mieke Steensels, Benedicte Lambrecht, Lionel Tafforeau, Caroline Demeret, Cyril Barbezange   +13 more
wiley   +1 more source

Representations of swine flu: Perspectives from a Malaysian pig farm [PDF]

, 2011
© The Author(s), 2010. This is the author's accepted manuscript. The final published article is available from the link below.Novel influenza viruses are seen, internationally, as posing considerable health challenges, but public responses to such ...
Hassan, SBS, Haque, S, Amreeta Dhanoa, Goodwin, R, Dhanoa, A, Sharifah Binti Syed Hassan, Shamsul Haque, Robin Goodwin   +7 more
core   +1 more source

Swine Influenza Virus (H1N2) Characterization and Transmission in Ferrets, Chile

Emerging Infectious Diseases, 2017
Phylogenetic analysis of the influenza hemagglutinin gene (HA) has suggested that commercial pigs in Chile harbor unique human seasonal H1-like influenza viruses, but further information, including characterization of these viruses, was unavailable.
Nicolás Bravo-Vasquez, Erik A. Karlsson, Pedro Jimenez-Bluhm, Victoria Meliopoulos, Bryan Kaplan, Shauna Marvin, Valerie Cortez, Pamela Freiden, Melinda A. Beck, Stacey Schultz-Cherry   +9 more
doaj   +1 more source

Genetic characterization and pathogenicity of a Eurasian avian-like H1N1 swine influenza reassortant virus

Virology Journal, 2022
Background Swine influenza viruses (SIV), considered the “mixing vessels” of influenza viruses, posed a significant threat to global health systems and are dangerous pathogens.
Hechao Zhu, Xiangmin Li, Huanchun Chen, Ping Qian   +3 more
doaj   +1 more source

Epidemic Status of Swine Influenza Virus in China [PDF]

Indian Journal of Microbiology, 2013
As one of the most significant swine diseases, in recent years, swine influenza (SI) has had an immense impact on public health and has raised extensive public concerns in China. Swine are predisposed to both avian and human influenza virus infections, between that and/or swine influenza viruses, genetic reassortment could occur.
Weili, Kong, Jiahui, Ye, Shangsong, Guan, Jinhua, Liu, Juan, Pu   +4 more
openaire   +2 more sources

Porcine circovirus 2 vaccination timing was not associated with piglets’ serological response

Veterinary Record, EarlyView.
Abstract Background The development of immunity in pigs starts in utero, but piglets are born immunologically immature and rely on maternal antibodies. Weaning exposes piglets to multiple stressors, yet vaccination is commonly performed around weaning.
Lea Uotinen, Sanna Nikunen, Gitte Blach Nielsen, Mari Heinonen   +3 more
wiley   +1 more source

Pandemic swine influenza virus: Preparedness planning [PDF]

, 2016
The novel H1N1 influenza virus that emerged in humans in Mexico in early 2009 and transmitted efficiently in the human population with global spread was declared a pandemic strain.
Ikenna, Onyedibe Kenneth, Ojogba, Okolo Mark, Aniefiok, Udoh Ubong, Clement, Daam   +3 more
core   +1 more source